Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults
Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved..
BACKGROUND: Genetic and environmental components may contribute to acne causation.
OBJECTIVE: We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne.
METHODS: We conducted a case-control study in dermatologic outpatient clinics in Italy. Cases (205) were consecutive those receiving a new diagnosis of moderate to severe acne. Control subjects (358) were people with no or mild acne, coming for a dermatologic consultation other than for acne.
RESULTS: Moderate to severe acne was strongly associated with a family history of acne in first-degree relatives (odds ratio 3.41, 95% confidence interval 2.31-5.05). The risk was reduced in people with lower body mass index with a more pronounced effect in male compared with female individuals. No association with smoking emerged. The risk increased with increased milk consumption (odds ratio 1.78, 95% confidence interval 1.22-2.59) in those consuming more than 3 portions per week. The association was more marked for skim than for whole milk. Consumption of fish was associated with a protective effect (odds ratio 0.68, 95% confidence interval 0.47-0.99). No association emerged between menstrual variables and acne risk.
LIMITATIONS: Some degree of overmatching may arise from choosing dermatologic control subjects and from inclusion of mild acne in the control group.
CONCLUSIONS: Family history, body mass index, and diet may influence the risk of moderate to severe acne. The influence of environmental and dietetic factors in acne should be further explored.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2012 |
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| Erschienen: |
2012 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:67 |
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| Enthalten in: |
Journal of the American Academy of Dermatology - 67(2012), 6 vom: 11. Dez., Seite 1129-35 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Di Landro, Anna [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 22.01.2013 Date Revised 09.04.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jaad.2012.02.018 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM215904494 |
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| 100 | 1 | |a Di Landro, Anna |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Family history, body mass index, selected dietary factors, menstrual history, and risk of moderate to severe acne in adolescents and young adults |
| 264 | 1 | |c 2012 | |
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| 500 | |a Date Completed 22.01.2013 | ||
| 500 | |a Date Revised 09.04.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2012 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: Genetic and environmental components may contribute to acne causation | ||
| 520 | |a OBJECTIVE: We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne | ||
| 520 | |a METHODS: We conducted a case-control study in dermatologic outpatient clinics in Italy. Cases (205) were consecutive those receiving a new diagnosis of moderate to severe acne. Control subjects (358) were people with no or mild acne, coming for a dermatologic consultation other than for acne | ||
| 520 | |a RESULTS: Moderate to severe acne was strongly associated with a family history of acne in first-degree relatives (odds ratio 3.41, 95% confidence interval 2.31-5.05). The risk was reduced in people with lower body mass index with a more pronounced effect in male compared with female individuals. No association with smoking emerged. The risk increased with increased milk consumption (odds ratio 1.78, 95% confidence interval 1.22-2.59) in those consuming more than 3 portions per week. The association was more marked for skim than for whole milk. Consumption of fish was associated with a protective effect (odds ratio 0.68, 95% confidence interval 0.47-0.99). No association emerged between menstrual variables and acne risk | ||
| 520 | |a LIMITATIONS: Some degree of overmatching may arise from choosing dermatologic control subjects and from inclusion of mild acne in the control group | ||
| 520 | |a CONCLUSIONS: Family history, body mass index, and diet may influence the risk of moderate to severe acne. The influence of environmental and dietetic factors in acne should be further explored | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Cazzaniga, Simone |e verfasserin |4 aut | |
| 700 | 1 | |a Parazzini, Fabio |e verfasserin |4 aut | |
| 700 | 1 | |a Ingordo, Vito |e verfasserin |4 aut | |
| 700 | 1 | |a Cusano, Francesco |e verfasserin |4 aut | |
| 700 | 1 | |a Atzori, Laura |e verfasserin |4 aut | |
| 700 | 1 | |a Cutrì, Francesco Tripodi |e verfasserin |4 aut | |
| 700 | 1 | |a Musumeci, Maria Letizia |e verfasserin |4 aut | |
| 700 | 1 | |a Zinetti, Cornelia |e verfasserin |4 aut | |
| 700 | 1 | |a Pezzarossa, Enrico |e verfasserin |4 aut | |
| 700 | 1 | |a Bettoli, Vincenzo |e verfasserin |4 aut | |
| 700 | 1 | |a Caproni, Marzia |e verfasserin |4 aut | |
| 700 | 1 | |a Lo Scocco, Giovanni |e verfasserin |4 aut | |
| 700 | 1 | |a Bonci, Angela |e verfasserin |4 aut | |
| 700 | 1 | |a Bencini, Pierluca |e verfasserin |4 aut | |
| 700 | 1 | |a Naldi, Luigi |e verfasserin |4 aut | |
| 700 | 0 | |a GISED Acne Study Group |e verfasserin |4 aut | |
| 700 | 1 | |a Cusano, Francesco |e investigator |4 oth | |
| 700 | 1 | |a Assunta, Errico |e investigator |4 oth | |
| 700 | 1 | |a Lanzoni, Anna |e investigator |4 oth | |
| 700 | 1 | |a Atzori, Laura |e investigator |4 oth | |
| 700 | 1 | |a Musumeci, Maria Letizia |e investigator |4 oth | |
| 700 | 1 | |a Micali, Giuseppe |e investigator |4 oth | |
| 700 | 1 | |a Pezzarossa, Enrico |e investigator |4 oth | |
| 700 | 1 | |a Bettoli, Vincenzo |e investigator |4 oth | |
| 700 | 1 | |a Virgili, Annarosa |e investigator |4 oth | |
| 700 | 1 | |a Caproni, Marzia |e investigator |4 oth | |
| 700 | 1 | |a Antiga, Emiliano |e investigator |4 oth | |
| 700 | 1 | |a Volpi, Walter |e investigator |4 oth | |
| 700 | 1 | |a Fabbri, Paolo |e investigator |4 oth | |
| 700 | 1 | |a Barbareschi, Mauro |e investigator |4 oth | |
| 700 | 1 | |a Cutrì, Francesco Tripodi |e investigator |4 oth | |
| 700 | 1 | |a Fabbrocini, Gabriella |e investigator |4 oth | |
| 700 | 1 | |a Lo Scocco, Giovanni |e investigator |4 oth | |
| 700 | 1 | |a Bonci, Angela |e investigator |4 oth | |
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| 700 | 1 | |a Licci, Nicola |e investigator |4 oth | |
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