Activity evaluation of components and preparation of effective components group of xiaoxuming decoction for anti-cerebral ischemic
OBJECTIVE: On basis of preliminary studies, to prepare the effective components group of Xiaoxuming decoction for anti-ischemic by combining chemical analysis with pharmacological activity screening.
METHOD: Free radical scavenging was assayed by DPPH method; the cell viability injured by hydrogen peroxide, L-glutamate, and hypoxia was determined by MTT assay; TBA method was used to determine mitochondrial lipid peroxidation.
RESULT: Comprehensive analysis of multi-target results, the comprehensive activities of 40% ethanol elution and the middle layer were the highest.
CONCLUSION: 40% ethanol elution and the middle layer were proportionally mixed as the effective components group of Xiaoxuming decoction.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2011 |
|---|---|
| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
|---|---|
| Enthalten in: |
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 36(2011), 15 vom: 29. Aug., Seite 2140-4 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Wang, Yuehua [VerfasserIn] |
|---|
| Themen: |
3KX376GY7L |
|---|
| Anmerkungen: |
Date Completed 09.12.2011 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM212877593 |
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| 100 | 1 | |a Wang, Yuehua |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Activity evaluation of components and preparation of effective components group of xiaoxuming decoction for anti-cerebral ischemic |
| 264 | 1 | |c 2011 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 09.12.2011 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: On basis of preliminary studies, to prepare the effective components group of Xiaoxuming decoction for anti-ischemic by combining chemical analysis with pharmacological activity screening | ||
| 520 | |a METHOD: Free radical scavenging was assayed by DPPH method; the cell viability injured by hydrogen peroxide, L-glutamate, and hypoxia was determined by MTT assay; TBA method was used to determine mitochondrial lipid peroxidation | ||
| 520 | |a RESULT: Comprehensive analysis of multi-target results, the comprehensive activities of 40% ethanol elution and the middle layer were the highest | ||
| 520 | |a CONCLUSION: 40% ethanol elution and the middle layer were proportionally mixed as the effective components group of Xiaoxuming decoction | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Drugs, Chinese Herbal |2 NLM | |
| 650 | 7 | |a Free Radical Scavengers |2 NLM | |
| 650 | 7 | |a Glutamic Acid |2 NLM | |
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| 650 | 7 | |a Hydrogen Peroxide |2 NLM | |
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| 700 | 1 | |a Qin, Hailin |e verfasserin |4 aut | |
| 700 | 1 | |a He, Xiaoli |e verfasserin |4 aut | |
| 700 | 1 | |a Du, Guanhua |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica |d 1989 |g 36(2011), 15 vom: 29. Aug., Seite 2140-4 |w (DE-627)NLM012733113 |x 1001-5302 |7 nnns |
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