Sex difference in performance in elevated plus maze and hippocampal GluR1 level
OBJECTIVE: To explore whether sex difference exists in the performance in each arm of elevated plus maze (EPM) and GluR1 level in the hippocampus of female and male Sprague-Dawley rats.
METHODS: Eleven male and 10 female SD rats were tested for 5 minutes in the EPM. These rats were decapitated 30 min after testing. The left and right hippocampus were dissected. Samples were stored at -80 degree for protein extracting. Western blot was used to detect the GluR1 levels in the hippocampus.
RESULTS: Female rats exhibited less anxiety-like behaviors than male rats in the EPM (P<0.05).Female rats had lower GluR1 levels in total and left hippocampus than those of male rats (P<0.05).
CONCLUSION: Sex difference exists between female and male rats in the EPM and hippocampal GluR1.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
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| Enthalten in: |
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 36(2011), 8 vom: 12. Aug., Seite 750-3 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Xiang, Xiaojun [VerfasserIn] |
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| Links: |
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| Themen: |
Glutamate receptor ionotropic, AMPA 1 |
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| Anmerkungen: |
Date Completed 15.10.2012 Date Revised 01.12.2018 published: Print Citation Status MEDLINE |
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| doi: |
10.3969/j.issn.1672-7347.2011.08.009 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM211660817 |
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| 100 | 1 | |a Xiang, Xiaojun |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Sex difference in performance in elevated plus maze and hippocampal GluR1 level |
| 264 | 1 | |c 2011 | |
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| 500 | |a Date Completed 15.10.2012 | ||
| 500 | |a Date Revised 01.12.2018 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To explore whether sex difference exists in the performance in each arm of elevated plus maze (EPM) and GluR1 level in the hippocampus of female and male Sprague-Dawley rats | ||
| 520 | |a METHODS: Eleven male and 10 female SD rats were tested for 5 minutes in the EPM. These rats were decapitated 30 min after testing. The left and right hippocampus were dissected. Samples were stored at -80 degree for protein extracting. Western blot was used to detect the GluR1 levels in the hippocampus | ||
| 520 | |a RESULTS: Female rats exhibited less anxiety-like behaviors than male rats in the EPM (P<0.05).Female rats had lower GluR1 levels in total and left hippocampus than those of male rats (P<0.05) | ||
| 520 | |a CONCLUSION: Sex difference exists between female and male rats in the EPM and hippocampal GluR1 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Receptors, AMPA |2 NLM | |
| 650 | 7 | |a glutamate receptor ionotropic, AMPA 1 |2 NLM | |
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| 700 | 1 | |a Hao, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Kosten, Therese A |e verfasserin |4 aut | |
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