Microstructural disruption of white matter in heroin addicts revealed by diffusion tensor imaging : a controlled study
OBJECTIVE: To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging (DTI).
METHODS: The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.
RESULTS: We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum.
CONCLUSION: The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2011 |
---|---|
Erschienen: |
2011 |
Enthalten in: |
Zur Gesamtaufnahme - volume:36 |
---|---|
Enthalten in: |
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 36(2011), 8 vom: 12. Aug., Seite 728-32 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Wang, Xuyi [VerfasserIn] |
---|
Links: |
---|
Themen: |
---|
Anmerkungen: |
Date Completed 15.10.2012 Date Revised 22.09.2011 published: Print Citation Status MEDLINE |
---|
doi: |
10.3969/j.issn.1672-7347.2011.08.005 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM211660779 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM211660779 | ||
003 | DE-627 | ||
005 | 20231224014019.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231224s2011 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3969/j.issn.1672-7347.2011.08.005 |2 doi | |
028 | 5 | 2 | |a pubmed24n0705.xml |
035 | |a (DE-627)NLM211660779 | ||
035 | |a (NLM)21937797 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Wang, Xuyi |e verfasserin |4 aut | |
245 | 1 | 0 | |a Microstructural disruption of white matter in heroin addicts revealed by diffusion tensor imaging |b a controlled study |
264 | 1 | |c 2011 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 15.10.2012 | ||
500 | |a Date Revised 22.09.2011 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a OBJECTIVE: To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging (DTI) | ||
520 | |a METHODS: The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls | ||
520 | |a RESULTS: We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum | ||
520 | |a CONCLUSION: The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
700 | 1 | |a Zhou, Xuhui |e verfasserin |4 aut | |
700 | 1 | |a Liao, Yanhui |e verfasserin |4 aut | |
700 | 1 | |a Tang, Jinsong |e verfasserin |4 aut | |
700 | 1 | |a Liu, Tieqiao |e verfasserin |4 aut | |
700 | 1 | |a Hao, Wei |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences |d 2004 |g 36(2011), 8 vom: 12. Aug., Seite 728-32 |w (DE-627)NLM155183753 |x 1672-7347 |7 nnns |
773 | 1 | 8 | |g volume:36 |g year:2011 |g number:8 |g day:12 |g month:08 |g pages:728-32 |
856 | 4 | 0 | |u http://dx.doi.org/10.3969/j.issn.1672-7347.2011.08.005 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 36 |j 2011 |e 8 |b 12 |c 08 |h 728-32 |