Microstructural disruption of white matter in heroin addicts revealed by diffusion tensor imaging : a controlled study

OBJECTIVE: To examine white matter integrity in heroin-dependent patients and matched normal controls with diffusion tensor imaging (DTI).

METHODS: The fractional anisotropy was compared between 15 heroin-dependent patients and 15 controls.

RESULTS: We found the fractional anisotropy was significantly decreased in specific brain regions of the heroin-dependent patients (P<0.001 uncorrected), including the frontal gyrus, the parietal lobule, the insula, and the corpus callosum.

CONCLUSION: The presence of microstructural abnormality is found in the white matter of several brain regions of heroin-dependent patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2011

Erschienen:

2011

Enthalten in:

Zur Gesamtaufnahme - volume:36

Enthalten in:

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 36(2011), 8 vom: 12. Aug., Seite 728-32

Sprache:

Englisch

Beteiligte Personen:

Wang, Xuyi [VerfasserIn]
Zhou, Xuhui [VerfasserIn]
Liao, Yanhui [VerfasserIn]
Tang, Jinsong [VerfasserIn]
Liu, Tieqiao [VerfasserIn]
Hao, Wei [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 15.10.2012

Date Revised 22.09.2011

published: Print

Citation Status MEDLINE

doi:

10.3969/j.issn.1672-7347.2011.08.005

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM211660779