Sensitization to ascaris lumbricoides and asthma severity in children
UNLABELLED: There is little information concerning asthma severity and sensitization to Ascaris lumbricoides in pediatric patients.
MATERIAL AND METHODS: The relationship between sensitization to Ascaris lumbricoides and asthma severity in 219 patients with a high prevalence of parasitic exposure (IgE antibodies) was studied by using linear, multivariate and logistic regression.
RESULTS: Sensitization to Ascaris lumbricoides was associated with positive skin tests for aeroallergens, increased total serum IgE, increased eosinophils, reductions in FEV1 and FEV1/FVC ratio, increased airway Methacholine, bronchodilator responsiveness, and hospitalizations for asthma in the past year.
CONCLUSIONS: Sensitization to Ascaris lumbricoides is associated with increased severity of asthma among Romanian children. This association is mediated by a high degree of atopy among the asthma children sensitized to Ascaris lumbricoides and belonging to a population with a low prevalence of helminthiasis.
Medienart: |
Artikel |
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Erscheinungsjahr: |
2011 |
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Erschienen: |
2011 |
Enthalten in: |
Zur Gesamtaufnahme - volume:115 |
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Enthalten in: |
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 115(2011), 2 vom: 01. Apr., Seite 387-91 |
Sprache: |
Rumänisch |
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Weiterer Titel: |
Influenţa ascaridiozei asupra severităţii astmului bronşic la copil |
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Beteiligte Personen: |
Rîpă, Carmen [VerfasserIn] |
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Themen: |
37341-29-0 |
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Anmerkungen: |
Date Completed 14.11.2011 Date Revised 29.08.2011 published: Print Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM211029416 |
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100 | 1 | |a Rîpă, Carmen |e verfasserin |4 aut | |
245 | 1 | 0 | |a Sensitization to ascaris lumbricoides and asthma severity in children |
246 | 3 | 3 | |a Influenţa ascaridiozei asupra severităţii astmului bronşic la copil |
264 | 1 | |c 2011 | |
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500 | |a Date Completed 14.11.2011 | ||
500 | |a Date Revised 29.08.2011 | ||
500 | |a published: Print | ||
500 | |a Citation Status MEDLINE | ||
520 | |a UNLABELLED: There is little information concerning asthma severity and sensitization to Ascaris lumbricoides in pediatric patients | ||
520 | |a MATERIAL AND METHODS: The relationship between sensitization to Ascaris lumbricoides and asthma severity in 219 patients with a high prevalence of parasitic exposure (IgE antibodies) was studied by using linear, multivariate and logistic regression | ||
520 | |a RESULTS: Sensitization to Ascaris lumbricoides was associated with positive skin tests for aeroallergens, increased total serum IgE, increased eosinophils, reductions in FEV1 and FEV1/FVC ratio, increased airway Methacholine, bronchodilator responsiveness, and hospitalizations for asthma in the past year | ||
520 | |a CONCLUSIONS: Sensitization to Ascaris lumbricoides is associated with increased severity of asthma among Romanian children. This association is mediated by a high degree of atopy among the asthma children sensitized to Ascaris lumbricoides and belonging to a population with a low prevalence of helminthiasis | ||
650 | 4 | |a English Abstract | |
650 | 4 | |a Journal Article | |
650 | 7 | |a Bronchodilator Agents |2 NLM | |
650 | 7 | |a Immunologic Factors |2 NLM | |
650 | 7 | |a Immunoglobulin E |2 NLM | |
650 | 7 | |a 37341-29-0 |2 NLM | |
700 | 1 | |a Bahnea, Roxana-Gabriela |e verfasserin |4 aut | |
700 | 1 | |a Cojocaru, Ingrid |e verfasserin |4 aut | |
700 | 1 | |a Luca, Mihaela Cătălina |e verfasserin |4 aut | |
700 | 1 | |a Leon, Maria |e verfasserin |4 aut | |
700 | 1 | |a Luca, Mariana |e verfasserin |4 aut | |
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