Myocardial strain assessment in cystic fibrosis
Copyright © 2011 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved..
BACKGROUND: The aim of this work was to evaluate myocardial strain analysis as a tool for the early detection of left ventricular functional changes in patients with cystic fibrosis.
METHODS: A total of 42 consecutive patients (mean age, 24 ± 7.5 years; 52% men) diagnosed with cystic fibrosis and referred for echocardiographic cardiac function assessment were prospectively enrolled. A group of healthy age-matched and gender-matched volunteers (n = 42) formed the reference population for echocardiographic comparisons.
RESULTS: Left ventricular ejection fraction was conserved in both groups but was significantly lower in the cystic fibrosis group. Cardiac function assessment using Doppler tissue imaging parameters revealed that both systolic and diastolic measurements differed between the two groups: mitral peak systolic and diastolic velocities, as well as septal and lateral wall strain rates, were decreased in patients with cystic fibrosis, as was longitudinal strain of both the septal and lateral walls.
CONCLUSIONS: Using strain measurements, subclinical changes in left ventricular function were found in patients with cystic fibrosis. These parameters were correlated with the degree of pulmonary involvement severity. These findings have potentially significant clinical implications for the outcomes and follow-up of patients with cystic fibrosis, meriting further studies.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
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| Enthalten in: |
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography - 24(2011), 9 vom: 10. Sept., Seite 1037-45 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Labombarda, Fabien [VerfasserIn] |
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| Anmerkungen: |
Date Completed 03.01.2012 Date Revised 21.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.echo.2011.06.004 |
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| PPN (Katalog-ID): |
NLM210005408 |
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| 245 | 1 | 0 | |a Myocardial strain assessment in cystic fibrosis |
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| 500 | |a Date Revised 21.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2011 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. | ||
| 520 | |a BACKGROUND: The aim of this work was to evaluate myocardial strain analysis as a tool for the early detection of left ventricular functional changes in patients with cystic fibrosis | ||
| 520 | |a METHODS: A total of 42 consecutive patients (mean age, 24 ± 7.5 years; 52% men) diagnosed with cystic fibrosis and referred for echocardiographic cardiac function assessment were prospectively enrolled. A group of healthy age-matched and gender-matched volunteers (n = 42) formed the reference population for echocardiographic comparisons | ||
| 520 | |a RESULTS: Left ventricular ejection fraction was conserved in both groups but was significantly lower in the cystic fibrosis group. Cardiac function assessment using Doppler tissue imaging parameters revealed that both systolic and diastolic measurements differed between the two groups: mitral peak systolic and diastolic velocities, as well as septal and lateral wall strain rates, were decreased in patients with cystic fibrosis, as was longitudinal strain of both the septal and lateral walls | ||
| 520 | |a CONCLUSIONS: Using strain measurements, subclinical changes in left ventricular function were found in patients with cystic fibrosis. These parameters were correlated with the degree of pulmonary involvement severity. These findings have potentially significant clinical implications for the outcomes and follow-up of patients with cystic fibrosis, meriting further studies | ||
| 650 | 4 | |a Comparative Study | |
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| 700 | 1 | |a Ellafi, Madiha |e verfasserin |4 aut | |
| 700 | 1 | |a Creveuil, C |e verfasserin |4 aut | |
| 700 | 1 | |a Ribault, Virginie |e verfasserin |4 aut | |
| 700 | 1 | |a Laurans, Murielle |e verfasserin |4 aut | |
| 700 | 1 | |a Guillot, Marcel |e verfasserin |4 aut | |
| 700 | 1 | |a Bergot, Emmanuel |e verfasserin |4 aut | |
| 700 | 1 | |a Grollier, Gilles |e verfasserin |4 aut | |
| 700 | 1 | |a Milliez, Paul |e verfasserin |4 aut | |
| 700 | 1 | |a Zalcman, Gérard |e verfasserin |4 aut | |
| 700 | 1 | |a Saloux, Eric |e verfasserin |4 aut | |
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