Combination therapy in pulmonary arterial hypertension : do we have the right strategy?
The management of pulmonary hypertension has already incorporated the use of multiple therapies into routine practice. Available therapies act principally through vasodilatation of the pulmonary arterial circulation through well-delineated mechanisms, although right ventricular function determines function and prognosis. Therefore, the goal of these therapies is effectively to preserve right ventricular function through reducing right ventricular afterload. The clinical trial experience of combination therapy is limited and the optimal combinations and administration strategies have yet to be clarified.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
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| Enthalten in: |
Expert review of respiratory medicine - 5(2011), 2 vom: 01. Apr., Seite 191-205 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Mukherjee, Bhashkar [VerfasserIn] |
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| Links: |
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| Themen: |
Antihypertensive Agents |
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| Anmerkungen: |
Date Completed 16.08.2011 Date Revised 20.11.2014 published: Print Citation Status MEDLINE |
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| doi: |
10.1586/ers.11.13 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM207642338 |
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| 520 | |a The management of pulmonary hypertension has already incorporated the use of multiple therapies into routine practice. Available therapies act principally through vasodilatation of the pulmonary arterial circulation through well-delineated mechanisms, although right ventricular function determines function and prognosis. Therefore, the goal of these therapies is effectively to preserve right ventricular function through reducing right ventricular afterload. The clinical trial experience of combination therapy is limited and the optimal combinations and administration strategies have yet to be clarified | ||
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