A case of complete response to S-1 plus CDDP in early-stage mucosal esophageal cancer
We report a case of early-stage mucosal esophageal cancer, showing a complete response to S-1 and cis-diamminedichloplatinum (CDDP). The patient was a 67-year-old man with synchronous double primary early-stage mucosal esophageal and advanced gastric cancer. We planned neoadjuvant chemotherapy with S-1 and CDDP for the advanced gastric cancer and endoscopic mucosal resection for the early-stage esophageal cancer. After the first course of chemotherapy, the endoscopy revealed that the esophageal cancer had become a normal mucosal lesion, and the biopsy was negative for cancer. We diagnosed a complete response to S-1 and CDDP in early-stage esophageal cancer. After two courses of chemotherapy, distal gastrectomy was performed. The patient is still alive with no sign of recurrence at 16 months after the disappearance of the original tumor. These results suggest that chemotherapy with S-1 plus CDDP may be effective in early-stage esophageal cancer.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:31 |
|---|---|
| Enthalten in: |
Anticancer research - 31(2011), 3 vom: 26. März, Seite 1019-22 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Takayama, Yuriko [VerfasserIn] |
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| Themen: |
150863-82-4 |
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| Anmerkungen: |
Date Completed 21.06.2011 Date Revised 25.11.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM207527822 |
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| 100 | 1 | |a Takayama, Yuriko |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A case of complete response to S-1 plus CDDP in early-stage mucosal esophageal cancer |
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| 520 | |a We report a case of early-stage mucosal esophageal cancer, showing a complete response to S-1 and cis-diamminedichloplatinum (CDDP). The patient was a 67-year-old man with synchronous double primary early-stage mucosal esophageal and advanced gastric cancer. We planned neoadjuvant chemotherapy with S-1 and CDDP for the advanced gastric cancer and endoscopic mucosal resection for the early-stage esophageal cancer. After the first course of chemotherapy, the endoscopy revealed that the esophageal cancer had become a normal mucosal lesion, and the biopsy was negative for cancer. We diagnosed a complete response to S-1 and CDDP in early-stage esophageal cancer. After two courses of chemotherapy, distal gastrectomy was performed. The patient is still alive with no sign of recurrence at 16 months after the disappearance of the original tumor. These results suggest that chemotherapy with S-1 plus CDDP may be effective in early-stage esophageal cancer | ||
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| 700 | 1 | |a Kochi, Mitsugu |e verfasserin |4 aut | |
| 700 | 1 | |a Fujii, Masashi |e verfasserin |4 aut | |
| 700 | 1 | |a Kanamori, Noriaki |e verfasserin |4 aut | |
| 700 | 1 | |a Kaiga, Teruo |e verfasserin |4 aut | |
| 700 | 1 | |a Mihara, Yoshiaki |e verfasserin |4 aut | |
| 700 | 1 | |a Miyazaki, Teruyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Tamegai, Hidenori |e verfasserin |4 aut | |
| 700 | 1 | |a Watanabe, Megumu |e verfasserin |4 aut | |
| 700 | 1 | |a Takayama, Tadatoshi |e verfasserin |4 aut | |
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