Low risk of recurrence in breast cancer with negative sentinel node
INTRODUCTION: The sentinel lymph node (SLN) procedure has emerged as a safe staging method with a low morbidity. The objective of the present study was to examine the recurrence rates including especially the axillary recurrence rate in SLN-negative patients after a long follow-up period.
MATERIAL AND METHODS: A total of 344 breast cancer patients were referred to SLN biopsy at our department from January 2000 to May 2005. Lymphoscintigraphy with (99m)Tc-nanocolloid was followed by same-day radioprobe-guided surgery. Among the 344 patients, 181 were SLN-negative. The group of SLN-negative patients was followed with regard to recurrence in general and axillary recurrence in particular by reviewing their respective medical files from control visits.
RESULTS: The identification rate (IR) was 99% (340/344). Extra-axillary SLNs were detected in seven patients (4%). One patient had an axillary recurrence 39 months after the primary operation, corresponding to an axillary recurrence rate of 0.6% after a median follow-up of 60 months (range 7-93).
CONCLUSION: With a high IR and an axillary recurrence rate of 0.6% after five years of follow-up, our data suggest that the SLN procedure is a valid and accurate method for the staging of breast cancer patients.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
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| Enthalten in: |
Danish medical bulletin - 58(2011), 4 vom: 06. Apr., Seite A4255 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hildebrandt, Malene Grubbe [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 25.08.2011 Date Revised 25.11.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM207227276 |
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| 100 | 1 | |a Hildebrandt, Malene Grubbe |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Low risk of recurrence in breast cancer with negative sentinel node |
| 264 | 1 | |c 2011 | |
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| 500 | |a Date Completed 25.08.2011 | ||
| 500 | |a Date Revised 25.11.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a INTRODUCTION: The sentinel lymph node (SLN) procedure has emerged as a safe staging method with a low morbidity. The objective of the present study was to examine the recurrence rates including especially the axillary recurrence rate in SLN-negative patients after a long follow-up period | ||
| 520 | |a MATERIAL AND METHODS: A total of 344 breast cancer patients were referred to SLN biopsy at our department from January 2000 to May 2005. Lymphoscintigraphy with (99m)Tc-nanocolloid was followed by same-day radioprobe-guided surgery. Among the 344 patients, 181 were SLN-negative. The group of SLN-negative patients was followed with regard to recurrence in general and axillary recurrence in particular by reviewing their respective medical files from control visits | ||
| 520 | |a RESULTS: The identification rate (IR) was 99% (340/344). Extra-axillary SLNs were detected in seven patients (4%). One patient had an axillary recurrence 39 months after the primary operation, corresponding to an axillary recurrence rate of 0.6% after a median follow-up of 60 months (range 7-93) | ||
| 520 | |a CONCLUSION: With a high IR and an axillary recurrence rate of 0.6% after five years of follow-up, our data suggest that the SLN procedure is a valid and accurate method for the staging of breast cancer patients | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Bartram, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Bak, Martin |e verfasserin |4 aut | |
| 700 | 1 | |a Højlund-Carlsen, Mette |e verfasserin |4 aut | |
| 700 | 1 | |a Petersen, Henrik |e verfasserin |4 aut | |
| 700 | 1 | |a Grupe, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Knoop, Ann |e verfasserin |4 aut | |
| 700 | 1 | |a Ryttov, Nis |e verfasserin |4 aut | |
| 700 | 1 | |a Højlund-Carlsen, Poul Flemming |e verfasserin |4 aut | |
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