Life-threatening hypokalaemia associated with ibuprofen-induced renal tubular acidosis
Renal tubular acidosis is an underreported complication of ibuprofen misuse, and can result in life-threatening hypokalaemia. We describe four patients who presented with profound hypokalaemia and muscle weakness associated with excessive ibuprofen ingestion. Ibuprofen cessation and supportive management resulted in complete biochemical resolution within a few days. These cases remind practitioners about potential complications of unmonitored use of over-the-counter analgesics, including those with potential for misuse due to their codeine content.
| Errataetall: |
CommentIn: Med J Aust. 2011 Jun 6;194(11):614. - PMID 21644884 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:194 |
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| Enthalten in: |
The Medical journal of Australia - 194(2011), 6 vom: 21. März, Seite 313-6 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ng, Jennifer L [VerfasserIn] |
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| Themen: |
Anti-Inflammatory Agents, Non-Steroidal |
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| Anmerkungen: |
Date Completed 03.06.2011 Date Revised 01.01.2021 published: Print CommentIn: Med J Aust. 2011 Jun 6;194(11):614. - PMID 21644884 Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM206844891 |
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| 500 | |a CommentIn: Med J Aust. 2011 Jun 6;194(11):614. - PMID 21644884 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Renal tubular acidosis is an underreported complication of ibuprofen misuse, and can result in life-threatening hypokalaemia. We describe four patients who presented with profound hypokalaemia and muscle weakness associated with excessive ibuprofen ingestion. Ibuprofen cessation and supportive management resulted in complete biochemical resolution within a few days. These cases remind practitioners about potential complications of unmonitored use of over-the-counter analgesics, including those with potential for misuse due to their codeine content | ||
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| 700 | 1 | |a Ong, Gregory S Y |e verfasserin |4 aut | |
| 700 | 1 | |a Prentice, David |e verfasserin |4 aut | |
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