Rapid deterioration of renal insufficiency after magnetic resonance imaging with gadolinium-based contrast agent
Gadolinium (Gd)-based contrast media were introduced as alternatives to iodinated media for magnetic resonance imaging (MRI). Although originally thought to be non-nephrotoxic, Gd-based contrast media have recently been reported to be associated with acute kidney injury. The underlying mechanism of Gd-induced renal injury is not completely understood. We report an 80-year-old patient with buccal mucosa cancer for whom MRI with Gd-based contrast agent was conducted 3 times within 3 weeks. The patient developed rapid deterioration of preexisting renal insufficiency, and developed uremic symptoms and pulmonary edema. The patient was hemodialyzed 3 times. This resulted in improvement of renal function and clinical symptoms. This case emphasizes the potential nephrotoxicity of Gd-based contrast media and suggests that renal insufficiency, diabetes mellitus, old age and high dose of Gd-based contrast medium are risk factors for acute kidney injury.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:75 |
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| Enthalten in: |
Clinical nephrology - 75(2011), 3 vom: 20. März, Seite 251-4 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Fujisaki, K [VerfasserIn] |
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| Themen: |
Case Reports |
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| Anmerkungen: |
Date Completed 19.04.2011 Date Revised 08.06.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM205944086 |
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| 245 | 1 | 0 | |a Rapid deterioration of renal insufficiency after magnetic resonance imaging with gadolinium-based contrast agent |
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| 520 | |a Gadolinium (Gd)-based contrast media were introduced as alternatives to iodinated media for magnetic resonance imaging (MRI). Although originally thought to be non-nephrotoxic, Gd-based contrast media have recently been reported to be associated with acute kidney injury. The underlying mechanism of Gd-induced renal injury is not completely understood. We report an 80-year-old patient with buccal mucosa cancer for whom MRI with Gd-based contrast agent was conducted 3 times within 3 weeks. The patient developed rapid deterioration of preexisting renal insufficiency, and developed uremic symptoms and pulmonary edema. The patient was hemodialyzed 3 times. This resulted in improvement of renal function and clinical symptoms. This case emphasizes the potential nephrotoxicity of Gd-based contrast media and suggests that renal insufficiency, diabetes mellitus, old age and high dose of Gd-based contrast medium are risk factors for acute kidney injury | ||
| 650 | 4 | |a Case Reports | |
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| 700 | 1 | |a Hirakawa, N |e verfasserin |4 aut | |
| 700 | 1 | |a Tsuruya, K |e verfasserin |4 aut | |
| 700 | 1 | |a Komune, S |e verfasserin |4 aut | |
| 700 | 1 | |a Iida, M |e verfasserin |4 aut | |
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