Factors associated with mortality in patients with exacerbation of chronic obstructive pulmonary disease hospitalized in General Medicine departments
We aim to improve knowledge on risk factors that relate to mortality in subjects with exacerbation of chronic obstructive pulmonary disease (COPD) who are hospitalized in General Medicine departments. In a cross-sectional multicenter study, by means of a logistic regression analysis, we assessed the possible association of death during hospitalization with the following groups of variables of participating patients: sociodemographic features, treatment received prior to admission and during hospitalization, COPD-related clinical features recorded prior to admission, comorbidity diagnosed prior to admission, clinical data recorded during hospitalization, laboratory results recorded during hospitalization, and electrocardiographic findings recorded during hospitalization. A total of 398 patients was included; 353 (88.7%) were male, and the median age of the patients was 75 years. Of these patients, 21 (5.3%) died during hospitalization. Only 270 (67.8%) received inhaled β(2) agonists during hospitalization, while 162 (40.7%) received angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. The median of predicted FEV(1) prior to admission was 42%. A total of 350 patients (87.9%) had been diagnosed with two or more comorbid conditions prior to admission. An association was found between increased risk of death during hospitalization and the previous diagnoses of pneumonia, coronary heart disease, and stroke. In conclusion, comorbidity is an important contributor to mortality among patients hospitalized in General Medicine departments because of COPD exacerbation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2011 |
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| Erschienen: |
2011 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:6 |
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| Enthalten in: |
Internal and emergency medicine - 6(2011), 1 vom: 28. Feb., Seite 47-54 |
| Sprache: |
Englisch |
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| Links: |
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| Anmerkungen: |
Date Completed 15.06.2011 Date Revised 20.10.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s11739-010-0465-7 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM201991543 |
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| 100 | 1 | |a Roca, Bernardino |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Factors associated with mortality in patients with exacerbation of chronic obstructive pulmonary disease hospitalized in General Medicine departments |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We aim to improve knowledge on risk factors that relate to mortality in subjects with exacerbation of chronic obstructive pulmonary disease (COPD) who are hospitalized in General Medicine departments. In a cross-sectional multicenter study, by means of a logistic regression analysis, we assessed the possible association of death during hospitalization with the following groups of variables of participating patients: sociodemographic features, treatment received prior to admission and during hospitalization, COPD-related clinical features recorded prior to admission, comorbidity diagnosed prior to admission, clinical data recorded during hospitalization, laboratory results recorded during hospitalization, and electrocardiographic findings recorded during hospitalization. A total of 398 patients was included; 353 (88.7%) were male, and the median age of the patients was 75 years. Of these patients, 21 (5.3%) died during hospitalization. Only 270 (67.8%) received inhaled β(2) agonists during hospitalization, while 162 (40.7%) received angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. The median of predicted FEV(1) prior to admission was 42%. A total of 350 patients (87.9%) had been diagnosed with two or more comorbid conditions prior to admission. An association was found between increased risk of death during hospitalization and the previous diagnoses of pneumonia, coronary heart disease, and stroke. In conclusion, comorbidity is an important contributor to mortality among patients hospitalized in General Medicine departments because of COPD exacerbation | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Multicenter Study | |
| 700 | 1 | |a Almagro, Pedro |e verfasserin |4 aut | |
| 700 | 1 | |a López, Francisco |e verfasserin |4 aut | |
| 700 | 1 | |a Cabrera, Francisco J |e verfasserin |4 aut | |
| 700 | 1 | |a Montero, Lorena |e verfasserin |4 aut | |
| 700 | 1 | |a Morchón, David |e verfasserin |4 aut | |
| 700 | 1 | |a Díez, Jesús |e verfasserin |4 aut | |
| 700 | 1 | |a de la Iglesia, Fernando |e verfasserin |4 aut | |
| 700 | 1 | |a Fernández, Mario |e verfasserin |4 aut | |
| 700 | 1 | |a Castiella, Jesús |e verfasserin |4 aut | |
| 700 | 1 | |a Zubillaga, Elena |e verfasserin |4 aut | |
| 700 | 1 | |a Recio, Jesús |e verfasserin |4 aut | |
| 700 | 1 | |a Soriano, Joan B |e verfasserin |4 aut | |
| 700 | 0 | |a ECCO Working Group on COPD |e verfasserin |4 aut | |
| 700 | 0 | |a Spanish Society of Internal Medicine |e verfasserin |4 aut | |
| 700 | 1 | |a de Rodas, Santiago Mola Caballero |e investigator |4 oth | |
| 700 | 1 | |a LópezGarcía, Francisco |e investigator |4 oth | |
| 700 | 1 | |a CarrataláTorregrosa, Jose Antonio |e investigator |4 oth | |
| 700 | 1 | |a PenadésCervera, Gemma |e investigator |4 oth | |
| 700 | 1 | |a CustardoyOlavarrieta, Juan |e investigator |4 oth | |
| 700 | 1 | |a MuelaMolinero, Alberto |e investigator |4 oth | |
| 700 | 1 | |a Galán, Juan Carlos Borrego |e investigator |4 oth | |
| 700 | 1 | |a Llanos, Rocío Llanos |e investigator |4 oth | |
| 700 | 1 | |a GarcíaOrenes, María del Carmen |e investigator |4 oth | |
| 700 | 1 | |a QuirogaIturralde, Juan Manuel |e investigator |4 oth | |
| 700 | 1 | |a ZubillagaGarmendia, Gabriel |e investigator |4 oth | |
| 700 | 1 | |a ZubillagaAzpiroz, Elena |e investigator |4 oth | |
| 700 | 1 | |a FernándezRuiz, Mario |e investigator |4 oth | |
| 700 | 1 | |a RecioIglesias, Jesús |e investigator |4 oth | |
| 700 | 1 | |a Velasco, María del Carmen Martínez |e investigator |4 oth | |
| 700 | 1 | |a Gutiérrez, María Paz Pérez |e investigator |4 oth | |
| 700 | 1 | |a Aguilar, Francisco Javier Cabrera |e investigator |4 oth | |
| 700 | 1 | |a Murua, Pablo Ryan |e investigator |4 oth | |
| 700 | 1 | |a OrizMinuesa, Juan Antonio |e investigator |4 oth | |
| 700 | 1 | |a Pérez-Barquero, Manuel Montero |e investigator |4 oth | |
| 700 | 1 | |a CastiellaHerrero, Jesús |e investigator |4 oth | |
| 700 | 1 | |a Portugal, Francisco José Sanjuan |e investigator |4 oth | |
| 700 | 1 | |a Salado, Juan Lucio Ramos |e investigator |4 oth | |
| 700 | 1 | |a Romero, José Barquero |e investigator |4 oth | |
| 700 | 1 | |a Lora, Fernando Javier Sánchez |e investigator |4 oth | |
| 700 | 1 | |a HortalTavira, Angel |e investigator |4 oth | |
| 700 | 1 | |a Nieto López Guerrero, Jerónimo |e investigator |4 oth | |
| 700 | 1 | |a Rivas, María Cruz Almendros |e investigator |4 oth | |
| 700 | 1 | |a de la IglesiaMartinez, Fernando |e investigator |4 oth | |
| 700 | 1 | |a Gutiérrez, Carlos Dueñas |e investigator |4 oth | |
| 700 | 1 | |a Polo, José Luis Lozano |e investigator |4 oth | |
| 700 | 1 | |a EscribanoSevillano, Dámaso |e investigator |4 oth | |
| 700 | 1 | |a Prado, Luis Quiroga |e investigator |4 oth | |
| 700 | 1 | |a Pérez, Carmen Mella |e investigator |4 oth | |
| 700 | 1 | |a Gabriel, Ramón Cigüenza |e investigator |4 oth | |
| 700 | 1 | |a Sánchez, José Portillo |e investigator |4 oth | |
| 700 | 1 | |a Boixeda i Viu, Ramon |e investigator |4 oth | |
| 700 | 1 | |a Rivas, Lorena Montero |e investigator |4 oth | |
| 700 | 1 | |a RománTerán, Carlos M |e investigator |4 oth | |
| 700 | 1 | |a Vila, Joan CarlesTrullas |e investigator |4 oth | |
| 700 | 1 | |a Villanueva, Bernardino Roca |e investigator |4 oth | |
| 700 | 1 | |a Julio Montes, Santiago |e investigator |4 oth | |
| 700 | 1 | |a Varela, José Manuel |e investigator |4 oth | |
| 700 | 1 | |a Morchón, David |e investigator |4 oth | |
| 700 | 1 | |a Escudero, Juan Carlos Martín |e investigator |4 oth | |
| 700 | 1 | |a DíezManglán, Jesús |e investigator |4 oth | |
| 700 | 1 | |a Güell i Farré, Elena |e investigator |4 oth | |
| 700 | 1 | |a AraújoLoperena, Olga |e investigator |4 oth | |
| 700 | 1 | |a Alvaro, NuriaGalofré |e investigator |4 oth | |
| 700 | 1 | |a Diaz, Beatriz Sobrino |e investigator |4 oth | |
| 700 | 1 | |a Gutiérrez, Ana Belen Mecina |e investigator |4 oth | |
| 700 | 1 | |a Pérez, María del Carmen Romero |e investigator |4 oth | |
| 700 | 1 | |a Otero, Patricia Crecente |e investigator |4 oth | |
| 700 | 1 | |a Cortés, Laura Madrigal |e investigator |4 oth | |
| 700 | 1 | |a Bandera, Rubén Díez |e investigator |4 oth | |
| 700 | 1 | |a Alamo, Verónica Alvarez |e investigator |4 oth | |
| 700 | 1 | |a Mena, Pedro Almagro |e investigator |4 oth | |
| 700 | 1 | |a Salamanca, Pablo Espejo |e investigator |4 oth | |
| 700 | 1 | |a GinerGalvañ, Vicente |e investigator |4 oth | |
| 700 | 1 | |a Rubio, Rafael Castillo |e investigator |4 oth | |
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