Study on antioxidant effect of Herba Lycopi and screening of active fractions
OBJECTIVE: To Study the antioxidant activity of Herba Lycopi, and screen the main active fractions.
METHOD: The different polar fractions were isolated from the ethanol extract of Herba Lycopi. The scavenging activity to DPPH and superoxide anions, reducing effect on Fe3+, and inhibiting activity of lipid peroxidation of the fractions were studied in vitro by high-throughput screening technique.
RESULT: The ethanol extract, ethyl acetate fraction (LLE-A. E, MCCM2921) and n-buthanol fraction (LLE-A. B, MCCM2922) of Herba Lycopi showed the scavenging activity to DPPH and superoxide anions, reducing effect on Fe3+, and inhibiting activity of lipid peroxidation.
CONCLUSION: The ethanol extract and different polar fractions showed antioxidant capacity in vitro. That may be explain that the effect of activating blood and dissolving stasis and anti-fibrosis of Herba Lycopi in traditional application. The results may be helpful for further development of Herba Lycopi as a low-toxic antioxidant drug.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
|---|---|
| Enthalten in: |
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica - 35(2010), 13 vom: 10. Juli, Seite 1754-7 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Nie, Bo [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 21.10.2010 Date Revised 11.11.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM201775247 |
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| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM201775247 | ||
| 003 | DE-627 | ||
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| 007 | tu | ||
| 008 | 231223s2010 xx ||||| 00| ||chi c | ||
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| 035 | |a (DE-627)NLM201775247 | ||
| 035 | |a (NLM)20862973 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a chi | ||
| 100 | 1 | |a Nie, Bo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Study on antioxidant effect of Herba Lycopi and screening of active fractions |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 21.10.2010 | ||
| 500 | |a Date Revised 11.11.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To Study the antioxidant activity of Herba Lycopi, and screen the main active fractions | ||
| 520 | |a METHOD: The different polar fractions were isolated from the ethanol extract of Herba Lycopi. The scavenging activity to DPPH and superoxide anions, reducing effect on Fe3+, and inhibiting activity of lipid peroxidation of the fractions were studied in vitro by high-throughput screening technique | ||
| 520 | |a RESULT: The ethanol extract, ethyl acetate fraction (LLE-A. E, MCCM2921) and n-buthanol fraction (LLE-A. B, MCCM2922) of Herba Lycopi showed the scavenging activity to DPPH and superoxide anions, reducing effect on Fe3+, and inhibiting activity of lipid peroxidation | ||
| 520 | |a CONCLUSION: The ethanol extract and different polar fractions showed antioxidant capacity in vitro. That may be explain that the effect of activating blood and dissolving stasis and anti-fibrosis of Herba Lycopi in traditional application. The results may be helpful for further development of Herba Lycopi as a low-toxic antioxidant drug | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Antioxidants |2 NLM | |
| 650 | 7 | |a Plant Extracts |2 NLM | |
| 700 | 1 | |a Huang, Feng |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Yong |e verfasserin |4 aut | |
| 700 | 1 | |a Du, Guanhua |e verfasserin |4 aut | |
| 700 | 1 | |a Liang, Xinmiao |e verfasserin |4 aut | |
| 700 | 1 | |a Xiao, Peigen |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica |d 1989 |g 35(2010), 13 vom: 10. Juli, Seite 1754-7 |w (DE-627)NLM012733113 |x 1001-5302 |7 nnns |
| 773 | 1 | 8 | |g volume:35 |g year:2010 |g number:13 |g day:10 |g month:07 |g pages:1754-7 |
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| 952 | |d 35 |j 2010 |e 13 |b 10 |c 07 |h 1754-7 | ||