Optimization of the extraction technology of total flavonoids from Mulgedium tataricum using response surface analysis
OBJECTIVE: Response surface analysis methodology (RSM) was used to optimize the extraction technology of total flavonoids from Mulgedium tataricum.
METHODS: Ethanol concentration, solvent-solid ratio, extraction temperature and extraction time were selected as influencing factors during extraction. The experiment mathematical model was arranged according to Box-Behnken central composite experiment design.
RESULTS: The optimal extraction conditions were as following: ethanol concentration 63.78%, solvent-solid ratio 40: 1, extraction temperature 90 degrees C, and extraction time 1.07 h, the predicted value of extraction rate of total flavonoids was 14.04% under the optimum conditions, and the experimental value was 13.79%.
CONCLUSION: The combination of Box-Behnken design and response surface analysis can well optimize the extraction technology of total flavonoids from Mulgedium tataricum.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
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| Enthalten in: |
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials - 33(2010), 4 vom: 01. Apr., Seite 621-4 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Gao, Yi-Xia [VerfasserIn] |
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| Themen: |
3K9958V90M |
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| Anmerkungen: |
Date Completed 01.03.2011 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM201609568 |
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| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
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| 041 | |a chi | ||
| 100 | 1 | |a Gao, Yi-Xia |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Optimization of the extraction technology of total flavonoids from Mulgedium tataricum using response surface analysis |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 01.03.2011 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: Response surface analysis methodology (RSM) was used to optimize the extraction technology of total flavonoids from Mulgedium tataricum | ||
| 520 | |a METHODS: Ethanol concentration, solvent-solid ratio, extraction temperature and extraction time were selected as influencing factors during extraction. The experiment mathematical model was arranged according to Box-Behnken central composite experiment design | ||
| 520 | |a RESULTS: The optimal extraction conditions were as following: ethanol concentration 63.78%, solvent-solid ratio 40: 1, extraction temperature 90 degrees C, and extraction time 1.07 h, the predicted value of extraction rate of total flavonoids was 14.04% under the optimum conditions, and the experimental value was 13.79% | ||
| 520 | |a CONCLUSION: The combination of Box-Behnken design and response surface analysis can well optimize the extraction technology of total flavonoids from Mulgedium tataricum | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Drugs, Chinese Herbal |2 NLM | |
| 650 | 7 | |a Flavonoids |2 NLM | |
| 650 | 7 | |a Solvents |2 NLM | |
| 650 | 7 | |a Ethanol |2 NLM | |
| 650 | 7 | |a 3K9958V90M |2 NLM | |
| 700 | 1 | |a Jing, Hong-Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Zu-Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Ji |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Sheng |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials |d 1997 |g 33(2010), 4 vom: 01. Apr., Seite 621-4 |w (DE-627)NLM09369914X |x 1001-4454 |7 nnns |
| 773 | 1 | 8 | |g volume:33 |g year:2010 |g number:4 |g day:01 |g month:04 |g pages:621-4 |
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