Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone : X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl
New complexes of dioxovanadium(V), zinc(II), ruthenium(II), palladium(II), and platinum(II) with 6-methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone (HmpETSC) have been synthesized. The composition of these complexes is discussed on the basis of elemental analyses, IR, Raman, NMR ((1)H, (13)C, and (31)P), and electronic spectral data. The X-ray crystal structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl] are also reported. The HmpETSC and its [Zn(HmpETSC)Cl(2)] and [Pd(mpETSC)Cl] complexes exhibit antineoplastic activity against colon cancer human cell lines (HCT 116).
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - year:2010 |
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| Enthalten in: |
Bioinorganic chemistry and applications - (2010) vom: 08., Seite 149149 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Elsayed, Shadia A [VerfasserIn] |
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Date Completed 14.07.2011 Date Revised 20.10.2021 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1155/2010/149149 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM199959218 |
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| 245 | 1 | 0 | |a Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone |b X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl |
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| 500 | |a Date Revised 20.10.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a New complexes of dioxovanadium(V), zinc(II), ruthenium(II), palladium(II), and platinum(II) with 6-methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone (HmpETSC) have been synthesized. The composition of these complexes is discussed on the basis of elemental analyses, IR, Raman, NMR ((1)H, (13)C, and (31)P), and electronic spectral data. The X-ray crystal structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl] are also reported. The HmpETSC and its [Zn(HmpETSC)Cl(2)] and [Pd(mpETSC)Cl] complexes exhibit antineoplastic activity against colon cancer human cell lines (HCT 116) | ||
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| 700 | 1 | |a Mostafa, Sahar I |e verfasserin |4 aut | |
| 700 | 1 | |a Jean-Claude, Bertrand J |e verfasserin |4 aut | |
| 700 | 1 | |a Todorova, Margarita |e verfasserin |4 aut | |
| 700 | 1 | |a Butler, Ian S |e verfasserin |4 aut | |
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