Recurrence incidence of small HCC in cirrhosis patients by ablation versus injection
BACKGROUND/AIMS: The incidence of local recurrence of hypervascular hepatocellular carcinoma (HCC) (15 mm or less) was compared retrospectively between a group treated with radiofrequency ablation (RFA) using cool-tip (Radionics, USA) 10-mm electrodes and a group treated with percutaneous ethanol injection (PEI).
METHODOLOGY: There were 23 patients who were treated for a total of 25 tumors during a 3-year period at our hospital. Ten of the tumors (11.1 +/- 2.7mm) were treated with RFA using cool-tip 10-mm electrodes and 15 tumors (10.6 +/- 2.7 mm) were treated with PEI. After treatment, progression was evaluated in enhanced CT scans every 3-6 months to confirm presence or absence of local recurrence.
RESULTS: The number of recurrences, mean observation period, and mean recurrence period in the RFA group were 2 (20%), 6.6 months, and 6 months. The number of recurrences, mean observation period, and mean recurrence period in the PEI group were 2 (13.3%), 19.1 months, and 18 months. The period between treatment and recurrence tended to be longer in the PEI group than in the RFA group to be significant p < 0.05.
CONCLUSIONS: The results suggest that PEI treatment is more effective in local treatment of hypervascular HCC with tumor diameters of 15 mm or less.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:57 |
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| Enthalten in: |
Hepato-gastroenterology - 57(2010), 98 vom: 25. März, Seite 195-201 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wakui, Noritaka [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 13.08.2010 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM199153140 |
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| 100 | 1 | |a Wakui, Noritaka |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Recurrence incidence of small HCC in cirrhosis patients by ablation versus injection |
| 264 | 1 | |c 2010 | |
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| 500 | |a Date Completed 13.08.2010 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND/AIMS: The incidence of local recurrence of hypervascular hepatocellular carcinoma (HCC) (15 mm or less) was compared retrospectively between a group treated with radiofrequency ablation (RFA) using cool-tip (Radionics, USA) 10-mm electrodes and a group treated with percutaneous ethanol injection (PEI) | ||
| 520 | |a METHODOLOGY: There were 23 patients who were treated for a total of 25 tumors during a 3-year period at our hospital. Ten of the tumors (11.1 +/- 2.7mm) were treated with RFA using cool-tip 10-mm electrodes and 15 tumors (10.6 +/- 2.7 mm) were treated with PEI. After treatment, progression was evaluated in enhanced CT scans every 3-6 months to confirm presence or absence of local recurrence | ||
| 520 | |a RESULTS: The number of recurrences, mean observation period, and mean recurrence period in the RFA group were 2 (20%), 6.6 months, and 6 months. The number of recurrences, mean observation period, and mean recurrence period in the PEI group were 2 (13.3%), 19.1 months, and 18 months. The period between treatment and recurrence tended to be longer in the PEI group than in the RFA group to be significant p < 0.05 | ||
| 520 | |a CONCLUSIONS: The results suggest that PEI treatment is more effective in local treatment of hypervascular HCC with tumor diameters of 15 mm or less | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Ethanol |2 NLM | |
| 650 | 7 | |a 3K9958V90M |2 NLM | |
| 700 | 1 | |a Iida, Kazunari |e verfasserin |4 aut | |
| 700 | 1 | |a Ikehara, Takashi |e verfasserin |4 aut | |
| 700 | 1 | |a Takayama, Ryuji |e verfasserin |4 aut | |
| 700 | 1 | |a Shiozawa, Kazue |e verfasserin |4 aut | |
| 700 | 1 | |a Takahashi, Masayoshi |e verfasserin |4 aut | |
| 700 | 1 | |a Nagai, Hidenari |e verfasserin |4 aut | |
| 700 | 1 | |a Watanabe, Manabu |e verfasserin |4 aut | |
| 700 | 1 | |a Ishii, Koji |e verfasserin |4 aut | |
| 700 | 1 | |a Igarashi, Yoshinori |e verfasserin |4 aut | |
| 700 | 1 | |a Sumino, Yasukiyo |e verfasserin |4 aut | |
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