A cognitive and affective pattern in posterior fossa strokes in children : a case series
AIM: Posterior fossa strokes account for about 10% of ischaemic strokes in children. Although motor and dysautonomic symptoms are common, to our knowledge cognitive and affective deficits have not been described in the paediatric literature. Our aim, therefore, was to describe these symptoms and deficits.
METHOD: In a retrospective study, we included all cases of posterior fossa strokes in children occurring at a single centre between 2005 and 2007, and investigated cognitive and affective deficits.
RESULTS: Five males aged 3 to 14 years met the inclusion criteria. They all presented very early with mood disturbances: outbursts of laughter and/or crying and alternating agitation or prostration that disappeared spontaneously within a few days. Persistent cognitive deficits were also diagnosed in all five: initial mutism, then anomia, followed by comprehension deficiency and deficiencies of planning ability, visual-spatial organization, and attention. Despite early and intensive rehabilitation, recovery from these cognitive deficits was slow and sometimes incomplete, and on follow-up they proved to be more disabling than the motor symptoms.
INTERPRETATION: These findings are similar to the cerebellar cognitive affective syndrome described in adults, and quite similar to the language and affective deficits observed in children after surgery for posterior fossa tumour. This is consistent with the role of the cerebellum and brainstem in affective and cognitive processes from early development.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2010 |
|---|---|
| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
|---|---|
| Enthalten in: |
Developmental medicine and child neurology - 52(2010), 7 vom: 07. Juli, Seite 626-31 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Kossorotoff, Manoelle [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
|---|
| Anmerkungen: |
Date Completed 20.07.2010 Date Revised 30.06.2010 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1111/j.1469-8749.2010.03616.x |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM197147593 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM197147593 | ||
| 003 | DE-627 | ||
| 005 | 20231223205946.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231223s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/j.1469-8749.2010.03616.x |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0657.xml |
| 035 | |a (DE-627)NLM197147593 | ||
| 035 | |a (NLM)20370817 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Kossorotoff, Manoelle |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A cognitive and affective pattern in posterior fossa strokes in children |b a case series |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 20.07.2010 | ||
| 500 | |a Date Revised 30.06.2010 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a AIM: Posterior fossa strokes account for about 10% of ischaemic strokes in children. Although motor and dysautonomic symptoms are common, to our knowledge cognitive and affective deficits have not been described in the paediatric literature. Our aim, therefore, was to describe these symptoms and deficits | ||
| 520 | |a METHOD: In a retrospective study, we included all cases of posterior fossa strokes in children occurring at a single centre between 2005 and 2007, and investigated cognitive and affective deficits | ||
| 520 | |a RESULTS: Five males aged 3 to 14 years met the inclusion criteria. They all presented very early with mood disturbances: outbursts of laughter and/or crying and alternating agitation or prostration that disappeared spontaneously within a few days. Persistent cognitive deficits were also diagnosed in all five: initial mutism, then anomia, followed by comprehension deficiency and deficiencies of planning ability, visual-spatial organization, and attention. Despite early and intensive rehabilitation, recovery from these cognitive deficits was slow and sometimes incomplete, and on follow-up they proved to be more disabling than the motor symptoms | ||
| 520 | |a INTERPRETATION: These findings are similar to the cerebellar cognitive affective syndrome described in adults, and quite similar to the language and affective deficits observed in children after surgery for posterior fossa tumour. This is consistent with the role of the cerebellum and brainstem in affective and cognitive processes from early development | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Gonin-Flambois, Coralie |e verfasserin |4 aut | |
| 700 | 1 | |a Gitiaux, Cyril |e verfasserin |4 aut | |
| 700 | 1 | |a Quijano, Susana |e verfasserin |4 aut | |
| 700 | 1 | |a Boddaert, Nathalie |e verfasserin |4 aut | |
| 700 | 1 | |a Bahi-Buisson, Nadia |e verfasserin |4 aut | |
| 700 | 1 | |a Barnerias, Christine |e verfasserin |4 aut | |
| 700 | 1 | |a Dulac, Olivier |e verfasserin |4 aut | |
| 700 | 1 | |a Brunelle, Francis |e verfasserin |4 aut | |
| 700 | 1 | |a Desguerre, Isabelle |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Developmental medicine and child neurology |d 1962 |g 52(2010), 7 vom: 07. Juli, Seite 626-31 |w (DE-627)NLM000156930 |x 1469-8749 |7 nnns |
| 773 | 1 | 8 | |g volume:52 |g year:2010 |g number:7 |g day:07 |g month:07 |g pages:626-31 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/j.1469-8749.2010.03616.x |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 52 |j 2010 |e 7 |b 07 |c 07 |h 626-31 | ||