Long-term stability of self-assembled monolayers on 316L stainless steel
316L stainless steel (316L SS) has been extensively used for making orthopedic, dental and cardiovascular implants. The use of phosphonic acid self-assembled monolayers (SAMs) on 316L SS has been previously explored for potential biomedical applications. In this study, we have investigated the long-term stability of methyl (-CH(3)) and carboxylic acid (-COOH)-terminated phosphonic acid SAMs on 316L under physiological conditions. The stability of SAMs on mechanically polished and electropolished 316L SS was also investigated as a part of this study. Well-ordered and uniform -CH(3)- and -COOH-terminated SAMs were coated on mechanically polished and electropolished 316L SS surfaces. The long-term stability of SAMs on 316L SS was investigated for up to 28 days in Tris-buffered saline (TBS) at 37 degrees C using x-ray photoelectron spectroscopy, atomic force microscopy and contact angle goniometry. A significant amount of phosphonic acid molecules was desorbed from the 316L SS surfaces within 1 to 7 days of TBS immersion followed by a slow desorption of molecules over the remaining days. The -COOH-terminated SAM was found to be more stable than the -CH(3)-terminated SAM on both mechanically and electropolished surfaces. No significant differences in the desorption behavior of SAMs were observed between mechanically and electropolished 316L SS surfaces.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2010 |
|---|---|
| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:5 |
|---|---|
| Enthalten in: |
Biomedical materials (Bristol, England) - 5(2010), 2 vom: 25. Apr., Seite 25008 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Kaufmann, C R [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
12597-68-1 |
|---|
| Anmerkungen: |
Date Completed 30.06.2010 Date Revised 29.03.2010 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1088/1748-6041/5/2/025008 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM196846633 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM196846633 | ||
| 003 | DE-627 | ||
| 005 | 20231223205348.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231223s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1088/1748-6041/5/2/025008 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0656.xml |
| 035 | |a (DE-627)NLM196846633 | ||
| 035 | |a (NLM)20339168 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Kaufmann, C R |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Long-term stability of self-assembled monolayers on 316L stainless steel |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 30.06.2010 | ||
| 500 | |a Date Revised 29.03.2010 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a 316L stainless steel (316L SS) has been extensively used for making orthopedic, dental and cardiovascular implants. The use of phosphonic acid self-assembled monolayers (SAMs) on 316L SS has been previously explored for potential biomedical applications. In this study, we have investigated the long-term stability of methyl (-CH(3)) and carboxylic acid (-COOH)-terminated phosphonic acid SAMs on 316L under physiological conditions. The stability of SAMs on mechanically polished and electropolished 316L SS was also investigated as a part of this study. Well-ordered and uniform -CH(3)- and -COOH-terminated SAMs were coated on mechanically polished and electropolished 316L SS surfaces. The long-term stability of SAMs on 316L SS was investigated for up to 28 days in Tris-buffered saline (TBS) at 37 degrees C using x-ray photoelectron spectroscopy, atomic force microscopy and contact angle goniometry. A significant amount of phosphonic acid molecules was desorbed from the 316L SS surfaces within 1 to 7 days of TBS immersion followed by a slow desorption of molecules over the remaining days. The -COOH-terminated SAM was found to be more stable than the -CH(3)-terminated SAM on both mechanically and electropolished surfaces. No significant differences in the desorption behavior of SAMs were observed between mechanically and electropolished 316L SS surfaces | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 7 | |a Coated Materials, Biocompatible |2 NLM | |
| 650 | 7 | |a Stainless Steel |2 NLM | |
| 650 | 7 | |a 12597-68-1 |2 NLM | |
| 700 | 1 | |a Mani, G |e verfasserin |4 aut | |
| 700 | 1 | |a Marton, D |e verfasserin |4 aut | |
| 700 | 1 | |a Johnson, D M |e verfasserin |4 aut | |
| 700 | 1 | |a Agrawal, C M |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Biomedical materials (Bristol, England) |d 2006 |g 5(2010), 2 vom: 25. Apr., Seite 25008 |w (DE-627)NLM179364588 |x 1748-605X |7 nnns |
| 773 | 1 | 8 | |g volume:5 |g year:2010 |g number:2 |g day:25 |g month:04 |g pages:25008 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1088/1748-6041/5/2/025008 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 5 |j 2010 |e 2 |b 25 |c 04 |h 25008 | ||