Effect of experimentally created occlusal disorders on the expression of estrogen in rat condylar cartilage
OBJECTIVE: To investigate the effect of experimentally created occlusal disorders (ECOD) on the expression of estrogen in rat condylar cartilage.
METHODS: The model of ECOD was created by moving right upper and left lower first molars anteriorly. The animals in ECOD were sacrificed at 2, 4, 6, 8 weeks later. In removed occlusal disorders group, the moved first molars were extracted at 6 weeks later, and the animals were sacrificed 2 weeks later. The expression of estrogen was detected by SABC technique of immunocytochemistry, and then was analyzed by the density of estrogen-positive chondrocytes.
RESULTS: 1) Estrogen was abundant in mature layer and hypertrophic layer of rat mandibular condylar cartilage. 2) In control group, the expression of estrogen decreased gradually from 6-week-old to 16-week-old. 3) In both childhood and puberty rats, the expression of estrogen in experiment group was significantly higher at 2 weeks after treatment, while no difference was found at 4, 6, 8 weeks after treatment. However, the expression in removed occlusal disorder group was higher than that in control group and 8 weeks of ECOD group.
CONCLUSION: In rat condylar cartilage, the expression of estrogen de-creases with age. Induced by ECOD, the expression of estrogen increases in early stage of remodelling activity.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
|---|---|
| Enthalten in: |
Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology - 27(2009), 5 vom: 29. Okt., Seite 561-4 |
| Sprache: |
Chinesisch |
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| Beteiligte Personen: |
Li, Bei [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 06.06.2015 Date Revised 01.12.2018 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM192961756 |
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| 100 | 1 | |a Li, Bei |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Effect of experimentally created occlusal disorders on the expression of estrogen in rat condylar cartilage |
| 264 | 1 | |c 2009 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 06.06.2015 | ||
| 500 | |a Date Revised 01.12.2018 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: To investigate the effect of experimentally created occlusal disorders (ECOD) on the expression of estrogen in rat condylar cartilage | ||
| 520 | |a METHODS: The model of ECOD was created by moving right upper and left lower first molars anteriorly. The animals in ECOD were sacrificed at 2, 4, 6, 8 weeks later. In removed occlusal disorders group, the moved first molars were extracted at 6 weeks later, and the animals were sacrificed 2 weeks later. The expression of estrogen was detected by SABC technique of immunocytochemistry, and then was analyzed by the density of estrogen-positive chondrocytes | ||
| 520 | |a RESULTS: 1) Estrogen was abundant in mature layer and hypertrophic layer of rat mandibular condylar cartilage. 2) In control group, the expression of estrogen decreased gradually from 6-week-old to 16-week-old. 3) In both childhood and puberty rats, the expression of estrogen in experiment group was significantly higher at 2 weeks after treatment, while no difference was found at 4, 6, 8 weeks after treatment. However, the expression in removed occlusal disorder group was higher than that in control group and 8 weeks of ECOD group | ||
| 520 | |a CONCLUSION: In rat condylar cartilage, the expression of estrogen de-creases with age. Induced by ECOD, the expression of estrogen increases in early stage of remodelling activity | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Estrogens |2 NLM | |
| 700 | 1 | |a Yu, Shi-bin |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Qi-hong |e verfasserin |4 aut | |
| 700 | 1 | |a Wen, Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Dong, Zhi-wei |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Mei-qing |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology |d 1997 |g 27(2009), 5 vom: 29. Okt., Seite 561-4 |w (DE-627)NLM113810970 |x 2618-0456 |7 nnns |
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