The effect of short-term aerobic training on coagulation and fibrinolytic factors in sedentary healthy postmenopausal women
OBJECTIVE: The purpose of this study was to assess the effect of short-term aerobic training on the fibrinolytic and coagulative factors in postmenopausal women.
STUDY DESIGN: Twenty volunteer sedentary healthy postmenopausal women (48-53 years), who entered the menopause naturally, were divided randomly into two groups: training (n=10) and control (n=10).
METHODS AND MAIN OUTCOME MEASURES: Training consisted of 10 sessions of submaximal aerobic cycling, 35 min for each session (5 min warm-up, 25 min aerobic training with 70% HRmax, 5 min active and 15 min passive recovery), 3 times a week. Coagulation and fibrinolytic factors were assessed both before and after aerobic program in both groups.
RESULTS: Fibrinogen, von Willbrand factor (vWF-Ag) antigen, plasminogen activator inhibitor-1 activity (PAI-1:Ac) and antigen (PAI-1:Ag) showed significant reduction after 10 sessions in the training group (P<0.05). Also after training, prothrombin time (PT), partial thromboplastin time (PTT), tissue plasminogen activator activity (tPA:Ac) and antigen (tPA:Ag) increased (P<0.05).
CONCLUSION: It was concluded that fibrinolytic activity on postmenopausal women could be improved by a 3-week regular submaximal training program. These changes on the hemostatic factors suggest that short-term aerobic training may prevent the decline in fibrinolytic function observed in sedentary postmenopausal women.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:64 |
|---|---|
| Enthalten in: |
Maturitas - 64(2009), 4 vom: 20. Dez., Seite 223-7 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jahangard, Tahereh [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 30.03.2010 Date Revised 01.12.2018 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.maturitas.2009.09.003 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM192279645 |
|---|
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| 100 | 1 | |a Jahangard, Tahereh |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effect of short-term aerobic training on coagulation and fibrinolytic factors in sedentary healthy postmenopausal women |
| 264 | 1 | |c 2009 | |
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| 500 | |a Date Completed 30.03.2010 | ||
| 500 | |a Date Revised 01.12.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: The purpose of this study was to assess the effect of short-term aerobic training on the fibrinolytic and coagulative factors in postmenopausal women | ||
| 520 | |a STUDY DESIGN: Twenty volunteer sedentary healthy postmenopausal women (48-53 years), who entered the menopause naturally, were divided randomly into two groups: training (n=10) and control (n=10) | ||
| 520 | |a METHODS AND MAIN OUTCOME MEASURES: Training consisted of 10 sessions of submaximal aerobic cycling, 35 min for each session (5 min warm-up, 25 min aerobic training with 70% HRmax, 5 min active and 15 min passive recovery), 3 times a week. Coagulation and fibrinolytic factors were assessed both before and after aerobic program in both groups | ||
| 520 | |a RESULTS: Fibrinogen, von Willbrand factor (vWF-Ag) antigen, plasminogen activator inhibitor-1 activity (PAI-1:Ac) and antigen (PAI-1:Ag) showed significant reduction after 10 sessions in the training group (P<0.05). Also after training, prothrombin time (PT), partial thromboplastin time (PTT), tissue plasminogen activator activity (tPA:Ac) and antigen (tPA:Ag) increased (P<0.05) | ||
| 520 | |a CONCLUSION: It was concluded that fibrinolytic activity on postmenopausal women could be improved by a 3-week regular submaximal training program. These changes on the hemostatic factors suggest that short-term aerobic training may prevent the decline in fibrinolytic function observed in sedentary postmenopausal women | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antigens |2 NLM | |
| 650 | 7 | |a Blood Coagulation Factors |2 NLM | |
| 650 | 7 | |a Plasminogen Activator Inhibitor 1 |2 NLM | |
| 650 | 7 | |a Von Willebrand antigen |2 NLM | |
| 650 | 7 | |a von Willebrand Factor |2 NLM | |
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| 700 | 1 | |a Ghoosheh, Babak |e verfasserin |4 aut | |
| 700 | 1 | |a Hedayati, Mehdi |e verfasserin |4 aut | |
| 700 | 1 | |a Dibaj, Azadeh |e verfasserin |4 aut | |
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