Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children
Gut bacteria contribute to energy conservation in man through their ability to ferment unabsorbed carbohydrate. The present study examined the composition of predominant faecal microbiota in obese and non-obese children. The participants (n 28) aged 11-14 years provided fresh faecal samples and completed a dietary survey consisting of 24 h diet recall and a FFQ of commonly used foods taken over the previous 3 months. Faecal bacteria were quantitated by real-time PCR using primers targeted at 16S rDNA. Of the participants, fifteen (seven female) were obese, with median BMI-for-age at the 99th percentile (range 97 to>99) while thirteen participants (seven female) were normal weight, with median BMI-for age being at the 50th percentile (range 1-85). Consumption of energy, carbohydrates, fat and protein was not significantly different between the obese and non-obese participants. There was no significant difference between the two groups in faecal levels of Bacteroides-Prevotella, Bifidobacterium species, Lactobacillus acidophilus group or Eubacterium rectale. Levels of Faecalibacterium prausnitzii were significantly higher in obese children than in non-obese participants (P = 0.0253). We concluded that the finding of increased numbers of F. prausnitzii in the faeces of obese children in south India adds to the growing information on alterations in faecal microbiota in obesity.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2010 |
|---|---|
| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:103 |
|---|---|
| Enthalten in: |
The British journal of nutrition - 103(2010), 3 vom: 23. Feb., Seite 335-8 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Balamurugan, Ramadass [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
DNA, Bacterial |
|---|
| Anmerkungen: |
Date Completed 17.02.2010 Date Revised 26.01.2010 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1017/S0007114509992182 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM192234196 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM192234196 | ||
| 003 | DE-627 | ||
| 005 | 20231223192623.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231223s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1017/S0007114509992182 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0641.xml |
| 035 | |a (DE-627)NLM192234196 | ||
| 035 | |a (NLM)19849869 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Balamurugan, Ramadass |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Quantitative differences in intestinal Faecalibacterium prausnitzii in obese Indian children |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 17.02.2010 | ||
| 500 | |a Date Revised 26.01.2010 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Gut bacteria contribute to energy conservation in man through their ability to ferment unabsorbed carbohydrate. The present study examined the composition of predominant faecal microbiota in obese and non-obese children. The participants (n 28) aged 11-14 years provided fresh faecal samples and completed a dietary survey consisting of 24 h diet recall and a FFQ of commonly used foods taken over the previous 3 months. Faecal bacteria were quantitated by real-time PCR using primers targeted at 16S rDNA. Of the participants, fifteen (seven female) were obese, with median BMI-for-age at the 99th percentile (range 97 to>99) while thirteen participants (seven female) were normal weight, with median BMI-for age being at the 50th percentile (range 1-85). Consumption of energy, carbohydrates, fat and protein was not significantly different between the obese and non-obese participants. There was no significant difference between the two groups in faecal levels of Bacteroides-Prevotella, Bifidobacterium species, Lactobacillus acidophilus group or Eubacterium rectale. Levels of Faecalibacterium prausnitzii were significantly higher in obese children than in non-obese participants (P = 0.0253). We concluded that the finding of increased numbers of F. prausnitzii in the faeces of obese children in south India adds to the growing information on alterations in faecal microbiota in obesity | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a DNA, Bacterial |2 NLM | |
| 650 | 7 | |a DNA, Ribosomal |2 NLM | |
| 650 | 7 | |a Dietary Carbohydrates |2 NLM | |
| 700 | 1 | |a George, Gemlyn |e verfasserin |4 aut | |
| 700 | 1 | |a Kabeerdoss, Jayakanthan |e verfasserin |4 aut | |
| 700 | 1 | |a Hepsiba, Jancy |e verfasserin |4 aut | |
| 700 | 1 | |a Chandragunasekaran, Aarthy M S |e verfasserin |4 aut | |
| 700 | 1 | |a Ramakrishna, Balakrishnan S |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t The British journal of nutrition |d 1947 |g 103(2010), 3 vom: 23. Feb., Seite 335-8 |w (DE-627)NLM000000434 |x 1475-2662 |7 nnns |
| 773 | 1 | 8 | |g volume:103 |g year:2010 |g number:3 |g day:23 |g month:02 |g pages:335-8 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1017/S0007114509992182 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 103 |j 2010 |e 3 |b 23 |c 02 |h 335-8 | ||