Aberrarone : a gorgonian-derived diterpene from Pseudopterogorgia elisabethae
A marine metabolite based on a previously undescribed carbon skeleton, aberrarone (1), is reported as a natural product from the Caribbean sea whip, Pseudopterogorgia elisabethae. The molecular structure of the crystalline metabolite was established by spectral analysis and subsequently confirmed by X-ray crystallographic analysis. Aberrarone shows in vitro antimalarial activity against a chloroquine-resistant strain of the protozoan parasite Plasmodium falciparum.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:74 |
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| Enthalten in: |
The Journal of organic chemistry - 74(2009), 19 vom: 02. Okt., Seite 7581-4 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rodríguez, Ileana I [VerfasserIn] |
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| Links: |
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| Themen: |
Aberrarone |
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| Anmerkungen: |
Date Completed 11.12.2009 Date Revised 12.03.2024 published: Print Citation Status MEDLINE |
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| doi: |
10.1021/jo901578r |
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| funding: |
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| PPN (Katalog-ID): |
NLM191200107 |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A marine metabolite based on a previously undescribed carbon skeleton, aberrarone (1), is reported as a natural product from the Caribbean sea whip, Pseudopterogorgia elisabethae. The molecular structure of the crystalline metabolite was established by spectral analysis and subsequently confirmed by X-ray crystallographic analysis. Aberrarone shows in vitro antimalarial activity against a chloroquine-resistant strain of the protozoan parasite Plasmodium falciparum | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Research Support, U.S. Gov't, Non-P.H.S. | |
| 650 | 7 | |a Antimalarials |2 NLM | |
| 650 | 7 | |a Biological Factors |2 NLM | |
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| 650 | 7 | |a aberrarone |2 NLM | |
| 700 | 1 | |a Rodríguez, Abimael D |e verfasserin |4 aut | |
| 700 | 1 | |a Zhao, Hong |e verfasserin |4 aut | |
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