Effects of cafeteria diet on the jejunum in sedentary and physically trained rats
Copyright (c) 2010 Elsevier Inc. All rights reserved..
OBJECTIVE: The effects of a cafeteria diet on the small intestine were investigated in adult Wistar rats under sedentary conditions and after physical training.
METHODS: Parameters including morphometry, enzyme activities, and total myenteric populations in the jejunum were evaluated.
RESULTS: The cafeteria diet, characterized as hyperlipidic, produced obese rats, corroborated by increases in the Lee index and the weights of the periepididymal and retroperitoneal adipose tissues (P<0.01). Obesity caused increases in the length of the small intestine, villi height, crypt depth, whole-wall thickness (P<0.05), and the enzymatic activities of alkaline phosphatase, lipase, and sucrase (P<0.01), in addition to a reduction in the number of goblet cells (P<0.05). With reference to the jejunal intrinsic innervations, the total number and area of myenteric neurons was unchanged regardless of the group. Physical training promoted 1) a reduction of the weight in the retroperitoneal and periepididymal adipose tissues (P<0.05) and 2) an increase in the thickness of the muscular layer (P<0.05).
CONCLUSION: The cafeteria diet promoted obesity in rodents, leading to alterations in morphometry and enzymatic intestinal parameters, which were partily attenuated by physical training.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Nutrition (Burbank, Los Angeles County, Calif.) - 26(2010), 3 vom: 05. März, Seite 312-20 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Scoaris, Célia Regina [VerfasserIn] |
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| Links: |
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| Themen: |
Dietary Carbohydrates |
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| Anmerkungen: |
Date Completed 14.07.2010 Date Revised 15.02.2010 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.nut.2009.04.012 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM190554096 |
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| 245 | 1 | 0 | |a Effects of cafeteria diet on the jejunum in sedentary and physically trained rats |
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| 500 | |a Date Completed 14.07.2010 | ||
| 500 | |a Date Revised 15.02.2010 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright (c) 2010 Elsevier Inc. All rights reserved. | ||
| 520 | |a OBJECTIVE: The effects of a cafeteria diet on the small intestine were investigated in adult Wistar rats under sedentary conditions and after physical training | ||
| 520 | |a METHODS: Parameters including morphometry, enzyme activities, and total myenteric populations in the jejunum were evaluated | ||
| 520 | |a RESULTS: The cafeteria diet, characterized as hyperlipidic, produced obese rats, corroborated by increases in the Lee index and the weights of the periepididymal and retroperitoneal adipose tissues (P<0.01). Obesity caused increases in the length of the small intestine, villi height, crypt depth, whole-wall thickness (P<0.05), and the enzymatic activities of alkaline phosphatase, lipase, and sucrase (P<0.01), in addition to a reduction in the number of goblet cells (P<0.05). With reference to the jejunal intrinsic innervations, the total number and area of myenteric neurons was unchanged regardless of the group. Physical training promoted 1) a reduction of the weight in the retroperitoneal and periepididymal adipose tissues (P<0.05) and 2) an increase in the thickness of the muscular layer (P<0.05) | ||
| 520 | |a CONCLUSION: The cafeteria diet promoted obesity in rodents, leading to alterations in morphometry and enzymatic intestinal parameters, which were partily attenuated by physical training | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Dietary Carbohydrates |2 NLM | |
| 650 | 7 | |a Dietary Fats |2 NLM | |
| 700 | 1 | |a Rizo, Gabriela Vasconcelos |e verfasserin |4 aut | |
| 700 | 1 | |a Roldi, Luciana Patrícia |e verfasserin |4 aut | |
| 700 | 1 | |a de Moraes, Solange Marta Franzói |e verfasserin |4 aut | |
| 700 | 1 | |a de Proença, André Ricardo Gomes |e verfasserin |4 aut | |
| 700 | 1 | |a Peralta, Rosane Marina |e verfasserin |4 aut | |
| 700 | 1 | |a Natali, Maria Raquel Marçal |e verfasserin |4 aut | |
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