Community-acquired methicillin-resistant Staphylococcus aureus as a cause of rapidly progressing pyelonephritis with pyonephrosis, necessitating emergent nephrectomy

In this article, we describe the first, to our knowledge, reported case of severe bacteremic upper urinary tract infection with pyonephrosis-in the context of prior chronic urinary tract disease-caused by community-acquired methicillin-resistant Staphylococcus aureus (MRSA). The patient presented with fever and constitutional symptoms, and computed tomography revealed extensive renal parenchymal infection along with a staghorn calculus and dilatation of the pyelocalyceal system. His clinical condition rapidly deteriorated, and he developed uncontrollable sepsis, necessitating an emergent nephrectomy. Significant pyonephrosis was noted during surgery. Blood cultures yielded MRSA, and molecular analysis (by polymerase chain reaction) of the MRSA strains from blood and wound fluid showed that they were Panton-Valentine leukocidin positive and they also possessed SCCmecA type IV. Postoperatively, the patient was treated with intravenous vancomycin for 3 weeks and had a favorable outcome.

Medienart:

E-Artikel

Erscheinungsjahr:

2009

Erschienen:

2009

Enthalten in:

Zur Gesamtaufnahme - volume:338

Enthalten in:

The American journal of the medical sciences - 338(2009), 3 vom: 02. Sept., Seite 233-5

Sprache:

Englisch

Beteiligte Personen:

Baraboutis, Ioannis G [VerfasserIn]
Koukoulaki, Maria [VerfasserIn]
Belesiotou, Helen [VerfasserIn]
Platsouka, Evaggelia [VerfasserIn]
Papastamopoulos, Vassilios [VerfasserIn]
Kontothanasis, Dimitrios [VerfasserIn]
Kontogianni-Katsarou, Katerina [VerfasserIn]
Tsagalou, Eleftheria P [VerfasserIn]
Paniara, Olga [VerfasserIn]
Skoutelis, Athanasios T [VerfasserIn]

Links:

Volltext

Themen:

6Q205EH1VU
Anti-Bacterial Agents
Case Reports
Journal Article
Vancomycin

Anmerkungen:

Date Completed 18.09.2009

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

doi:

10.1097/MAJ.0b013e3181a778fd

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM190274735