Quantitative right and left ventricular functional analysis during gated whole-chest MDCT : a feasibility study comparing automatic segmentation to semi-manual contouring
Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved..
PURPOSE: To evaluate the feasibility of an automatic, whole-heart segmentation algorithm for measuring global heart function from gated, whole-chest MDCT images.
MATERIAL AND METHODS: 15 patients with suspicion of PE underwent whole-chest contrast-enhanced MDCT with retrospective ECG synchronization. Two observers computed right and left ventricular functional indices using a semi-manual and an automatic whole-heart segmentation algorithm. The two techniques were compared using Bland-Altman analysis and paired Student's t-test. Measurement reproducibility was calculated using intraclass correlation coefficient.
RESULTS: Ventricular analysis with automatic segmentation was successful in 13/15 (86%) and in 15/15 (100%) patients for the right ventricle and left ventricle, respectively. Reproducibility of measurements for both ventricles was perfect (ICC: 1.00) and very good for automatic and semi-manual measurements, respectively. Ventricular volumes and functional indices except right ventricular ejection fraction obtained from the automatic method were significantly higher for the RV compared to the semi-manual methods.
CONCLUSIONS: The automatic, whole-heart segmentation algorithm enabled highly reproducible global heart function to be rapidly obtained in patients undergoing gated whole-chest MDCT for assessment of acute chest pain with suspicion of pulmonary embolism.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2010 |
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| Erschienen: |
2010 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:74 |
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| Enthalten in: |
European journal of radiology - 74(2010), 3 vom: 10. Juni, Seite e138-43 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Coche, Emmanuel [VerfasserIn] |
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| Anmerkungen: |
Date Completed 11.01.2011 Date Revised 25.11.2016 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.ejrad.2009.05.037 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM189419385 |
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| 100 | 1 | |a Coche, Emmanuel |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Quantitative right and left ventricular functional analysis during gated whole-chest MDCT |b a feasibility study comparing automatic segmentation to semi-manual contouring |
| 264 | 1 | |c 2010 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
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| 500 | |a Date Completed 11.01.2011 | ||
| 500 | |a Date Revised 25.11.2016 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved. | ||
| 520 | |a PURPOSE: To evaluate the feasibility of an automatic, whole-heart segmentation algorithm for measuring global heart function from gated, whole-chest MDCT images | ||
| 520 | |a MATERIAL AND METHODS: 15 patients with suspicion of PE underwent whole-chest contrast-enhanced MDCT with retrospective ECG synchronization. Two observers computed right and left ventricular functional indices using a semi-manual and an automatic whole-heart segmentation algorithm. The two techniques were compared using Bland-Altman analysis and paired Student's t-test. Measurement reproducibility was calculated using intraclass correlation coefficient | ||
| 520 | |a RESULTS: Ventricular analysis with automatic segmentation was successful in 13/15 (86%) and in 15/15 (100%) patients for the right ventricle and left ventricle, respectively. Reproducibility of measurements for both ventricles was perfect (ICC: 1.00) and very good for automatic and semi-manual measurements, respectively. Ventricular volumes and functional indices except right ventricular ejection fraction obtained from the automatic method were significantly higher for the RV compared to the semi-manual methods | ||
| 520 | |a CONCLUSIONS: The automatic, whole-heart segmentation algorithm enabled highly reproducible global heart function to be rapidly obtained in patients undergoing gated whole-chest MDCT for assessment of acute chest pain with suspicion of pulmonary embolism | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Walker, Matthew J |e verfasserin |4 aut | |
| 700 | 1 | |a Zech, Francis |e verfasserin |4 aut | |
| 700 | 1 | |a de Crombrugghe, Rodolphe |e verfasserin |4 aut | |
| 700 | 1 | |a Vlassenbroek, Alain |e verfasserin |4 aut | |
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