Recovery of anti-Toxoplasma gondii immunoglobulin M in stored guthrie card blood spots
Retrospective testing of neonatal Guthrie card blood spots for specific immunoglobulin M (IgM) can distinguish congenital toxoplasmosis from acquired toxoplasmosis. We determined whether storage temperature reduced IgM detection, using filter paper blood samples "spiked" with anti-Toxoplasma IgM. After 300 days, IgM detection deteriorated with storage at room temperature but not at temperatures of 4 degrees C or lower.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2009 |
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Erschienen: |
2009 |
Enthalten in: |
Zur Gesamtaufnahme - volume:47 |
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Enthalten in: |
Journal of clinical microbiology - 47(2009), 8 vom: 01. Aug., Seite 2626-8 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Tan, Hooi-Kuan [VerfasserIn] |
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Links: |
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Themen: |
Antibodies, Bacterial |
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Anmerkungen: |
Date Completed 28.09.2009 Date Revised 28.10.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1128/JCM.00893-09 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM189014911 |
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520 | |a Retrospective testing of neonatal Guthrie card blood spots for specific immunoglobulin M (IgM) can distinguish congenital toxoplasmosis from acquired toxoplasmosis. We determined whether storage temperature reduced IgM detection, using filter paper blood samples "spiked" with anti-Toxoplasma IgM. After 300 days, IgM detection deteriorated with storage at room temperature but not at temperatures of 4 degrees C or lower | ||
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