Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients : Part II. Treatment
BACKGROUND: Invasive candidiasis and candidemia are frequently encountered in the nosocomial setting particularly in the intensive care unit (ICU).
OBJECTIVE AND METHODS: To review the current management of invasive candidiasis and candidemia in non-neutropenic adult ICU patients based on a review of the literature and an European expert panel discussion.
RESULTS AND CONCLUSIONS: Empiric and directed treatment for invasive candidiasis are predicated on the hemodynamic status of the patient. Unstable patients may benefit from broad-spectrum antifungal agents, which can be narrowed once the patient has stabilized and the identity of the infecting species is established. In stable patients, a more classical approach using fluconazole may be satisfactory provided that the patient is not colonized with fluconazole resistant strains or there has been recent past exposure to an azole (<30 days). In contrast, pre-emptive therapy is based on the presence of surrogate markers.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:35 |
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| Enthalten in: |
Intensive care medicine - 35(2009), 2 vom: 21. Feb., Seite 206-14 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Guery, Benoît P [VerfasserIn] |
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| Links: |
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| Themen: |
7XU7A7DROE |
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| Anmerkungen: |
Date Completed 04.08.2009 Date Revised 13.11.2018 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00134-008-1339-6 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM184168082 |
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| 100 | 1 | |a Guery, Benoît P |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Management of invasive candidiasis and candidemia in adult non-neutropenic intensive care unit patients |b Part II. Treatment |
| 264 | 1 | |c 2009 | |
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| 500 | |a Date Completed 04.08.2009 | ||
| 500 | |a Date Revised 13.11.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Invasive candidiasis and candidemia are frequently encountered in the nosocomial setting particularly in the intensive care unit (ICU) | ||
| 520 | |a OBJECTIVE AND METHODS: To review the current management of invasive candidiasis and candidemia in non-neutropenic adult ICU patients based on a review of the literature and an European expert panel discussion | ||
| 520 | |a RESULTS AND CONCLUSIONS: Empiric and directed treatment for invasive candidiasis are predicated on the hemodynamic status of the patient. Unstable patients may benefit from broad-spectrum antifungal agents, which can be narrowed once the patient has stabilized and the identity of the infecting species is established. In stable patients, a more classical approach using fluconazole may be satisfactory provided that the patient is not colonized with fluconazole resistant strains or there has been recent past exposure to an azole (<30 days). In contrast, pre-emptive therapy is based on the presence of surrogate markers | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Antifungal Agents |2 NLM | |
| 650 | 7 | |a Amphotericin B |2 NLM | |
| 650 | 7 | |a 7XU7A7DROE |2 NLM | |
| 650 | 7 | |a Fluconazole |2 NLM | |
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| 700 | 1 | |a Arendrup, Maiken C |e verfasserin |4 aut | |
| 700 | 1 | |a Auzinger, Georg |e verfasserin |4 aut | |
| 700 | 1 | |a Azoulay, Elie |e verfasserin |4 aut | |
| 700 | 1 | |a Borges Sá, Márcio |e verfasserin |4 aut | |
| 700 | 1 | |a Johnson, Elizabeth M |e verfasserin |4 aut | |
| 700 | 1 | |a Müller, Eckhard |e verfasserin |4 aut | |
| 700 | 1 | |a Putensen, Christian |e verfasserin |4 aut | |
| 700 | 1 | |a Rotstein, Coleman |e verfasserin |4 aut | |
| 700 | 1 | |a Sganga, Gabriele |e verfasserin |4 aut | |
| 700 | 1 | |a Venditti, Mario |e verfasserin |4 aut | |
| 700 | 1 | |a Zaragoza Crespo, Rafael |e verfasserin |4 aut | |
| 700 | 1 | |a Kullberg, Bart Jan |e verfasserin |4 aut | |
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