Agreement between optical coherence tomography and digital stereophotography in vertical cup-to-disc ratio measurement
BACKGROUND: Given the increasing popularity of optical coherence tomography in the diagnosis of glaucoma, we aimed to assess agreement between StratusOCT and stereophotography in measuring the vertical cup-to-disc ratio (VCDR) and examine whether it can be improved by changing the StratusOCT cup-offset.
METHODS: In group 1 (79 eyes), VCDR measurements obtained by StratusOCT (using the default cup-offset of 150 microm above the retinal pigment epithelium) and stereophotography were compared. For each eye, the cup-offset was moved upward or downward until the difference disappeared and an adjusted cup-offset was identified. In group 2 (41 eyes), the stereophotography VCDR was compared to the StratusOCT value obtained by using the mean adjusted cup-offset. StratusOCT was used to classify optic disc cups as shallow or deep.
RESULTS: In group 1, StratusOCT overestimated VCDR in optic discs with deep cups and underestimated it in those with shallow cups (p < 0.0001). Mean adjusted cup-offsets were 72.8 +/- 92 microm and 191.6 +/- 70 microm for eyes with deep and shallow cups. The 95% limits of agreement (LOA) ranged from -0.21 to 0.17. In group 2, the adjusted cup-offsets enabled us to eliminate the statistical differences in VCDR measurements and improve the 95% LOA (from -0.13 to 0.14).
CONCLUSION: Adjusting the StratusOCT cup-offset according to the cup depth improves agreement between StratusOCT and stereophotography in measuring the VCDR.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2009 |
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| Erschienen: |
2009 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:247 |
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| Enthalten in: |
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 247(2009), 3 vom: 25. März, Seite 377-83 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Savini, Giacomo [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 25.03.2009 Date Revised 13.11.2018 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00417-008-0968-3 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM184034450 |
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| 100 | 1 | |a Savini, Giacomo |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Agreement between optical coherence tomography and digital stereophotography in vertical cup-to-disc ratio measurement |
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| 500 | |a Date Completed 25.03.2009 | ||
| 500 | |a Date Revised 13.11.2018 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Given the increasing popularity of optical coherence tomography in the diagnosis of glaucoma, we aimed to assess agreement between StratusOCT and stereophotography in measuring the vertical cup-to-disc ratio (VCDR) and examine whether it can be improved by changing the StratusOCT cup-offset | ||
| 520 | |a METHODS: In group 1 (79 eyes), VCDR measurements obtained by StratusOCT (using the default cup-offset of 150 microm above the retinal pigment epithelium) and stereophotography were compared. For each eye, the cup-offset was moved upward or downward until the difference disappeared and an adjusted cup-offset was identified. In group 2 (41 eyes), the stereophotography VCDR was compared to the StratusOCT value obtained by using the mean adjusted cup-offset. StratusOCT was used to classify optic disc cups as shallow or deep | ||
| 520 | |a RESULTS: In group 1, StratusOCT overestimated VCDR in optic discs with deep cups and underestimated it in those with shallow cups (p < 0.0001). Mean adjusted cup-offsets were 72.8 +/- 92 microm and 191.6 +/- 70 microm for eyes with deep and shallow cups. The 95% limits of agreement (LOA) ranged from -0.21 to 0.17. In group 2, the adjusted cup-offsets enabled us to eliminate the statistical differences in VCDR measurements and improve the 95% LOA (from -0.13 to 0.14) | ||
| 520 | |a CONCLUSION: Adjusting the StratusOCT cup-offset according to the cup depth improves agreement between StratusOCT and stereophotography in measuring the VCDR | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Espana, Edgar M |e verfasserin |4 aut | |
| 700 | 1 | |a Acosta, Ana Carolina |e verfasserin |4 aut | |
| 700 | 1 | |a Carbonelli, Michele |e verfasserin |4 aut | |
| 700 | 1 | |a Bellusci, Costantino |e verfasserin |4 aut | |
| 700 | 1 | |a Barboni, Piero |e verfasserin |4 aut | |
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