HIV infection of the central nervous system : clinical features and neuropathogenesis
Almost 65 million people worldwide have been infected with HIV since it was first identified in the early 1980s. Neurologic disorders associated with HIV type 1 affect between 40% and 70% of infected individuals. The most significant of these disorders include HIV-associated neurocognitive disorder, which comprises HIV-associated dementia, mild neurocognitive disorder, and asymptomatic neurocognitive impairment. Despite the availability of combination antiretroviral therapy, HIV-related central nervous system disorders continue to represent a substantial personal, economic, and societal burden. This review summarizes the clinical manifestations, diagnosis, treatment, and pathogenesis of the primary HIV-associated central nervous system disorders.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2008 |
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| Erschienen: |
2008 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:26 |
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| Enthalten in: |
Neurologic clinics - 26(2008), 3 vom: 26. Aug., Seite 799-819, x |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Boissé, Lysa [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 21.10.2008 Date Revised 16.11.2017 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.ncl.2008.04.002 |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM181192551 |
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| 520 | |a Almost 65 million people worldwide have been infected with HIV since it was first identified in the early 1980s. Neurologic disorders associated with HIV type 1 affect between 40% and 70% of infected individuals. The most significant of these disorders include HIV-associated neurocognitive disorder, which comprises HIV-associated dementia, mild neurocognitive disorder, and asymptomatic neurocognitive impairment. Despite the availability of combination antiretroviral therapy, HIV-related central nervous system disorders continue to represent a substantial personal, economic, and societal burden. This review summarizes the clinical manifestations, diagnosis, treatment, and pathogenesis of the primary HIV-associated central nervous system disorders | ||
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