Efficacy of sumamigren at early and late stages of migraine attack

Three migraine attacks have been studied in 30 patients aged 39.4+/-10.5 years. A significant decrease of headache and concomitant symptoms was found 1, 2 and 6 h after receiving of sumamigren (sumatriptan). The drug was effective in 2 out of 3 attacks in most of the patients (53.3%); in 3 attacks--in 26.7%; in 1 attack--in 6.7%. In 13.3% of the patients the drug did not exert a therapeutic effect. When administering at the early stage of the attack, the drug reduced the headache after 1 and 2 h more significantly comparing to patients receiving it at the later stage. In case of early prescription of sumamigren, the relapse of headache was observed in 7,8% and in later one--in 20.5% of patients. During the first 24 h of attack, patients switched to the drug at the early stage reported higher quality of life (mean score 45.1+/-14.6) than those with later prescription (71.4+/-18.3). It has been concluded that sumamigren is an effective medication for stopping the migraine attack, in particular at its the beginning.

Medienart:

Artikel

Erscheinungsjahr:

2007

Erschienen:

2007

Enthalten in:

Zur Gesamtaufnahme - volume:107

Enthalten in:

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 107(2007), 8 vom: 01., Seite 29-33

Sprache:

Russisch

Beteiligte Personen:

Tabeeva, G R [VerfasserIn]
Azimova, Iu E [VerfasserIn]

Themen:

8R78F6L9VO
Comparative Study
English Abstract
Journal Article
Multicenter Study
Serotonin Receptor Agonists
Sumatriptan

Anmerkungen:

Date Completed 02.09.2008

Date Revised 18.10.2016

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM178613835