Nutrition, adiposity and health

Calorie intake is an important determinant of health. Excessive energy intake is associated with abdominal obesity, type 2 diabetes, cardiovascular disease, cancer, and premature mortality. Calorie restriction (CR) without malnutrition increases maximal lifespan by preventing many age-associated chronic diseases and by preserving function at more youthful-like states in rodents. In overweight and obese humans CR improves metabolic health and reduced mortality for type 2 diabetes, cardiovascular disease and cancer. In middle-aged healthy lean individuals CR causes many of the same cardiometabolic adaptations that occur in long-lived CR rodents, including decreased metabolic, inflammatory, and hormonal risk factors for diabetes, hypertension, cardiovascular disease and cancer Protein and polyphenols intake, and physical activity may have additional beneficial effects in preventing diseases and promoting health. Additional studies are needed to identify the precise calorie, protein and polyphenols intake and amount of exercise needed for optimal health in each individual, depending on his/her age, sex and genetic background.

Medienart:

Artikel

Erscheinungsjahr:

2007

Erschienen:

2007

Enthalten in:

Zur Gesamtaufnahme - volume:31

Enthalten in:

Epidemiologia e prevenzione - 31(2007), 5 vom: 31. Sept., Seite 290-4

Sprache:

Italienisch

Weiterer Titel:

Nutrizione, adiposità e salute

Beteiligte Personen:

Fontana, Luigi [VerfasserIn]

Themen:

English Abstract
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 04.04.2008

Date Revised 20.10.2021

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM177612827