Remineralization of artificial interproximal carious lesions using a fluoride mouthrinse

PURPOSE: To evaluate remineralization and fluoride uptake of demineralized enamel specimens in artificial interproximal spaces using a 250 ppm fluoride mouthrinse (100 ppm amine fluoride and 150 ppm sodium fluoride) compared to a placebo-mouthrinse.

METHODS: This was a two-way, double-blind, in situ study. 24 volunteers wore intraoral appliances in the lower jaw with mounted demineralized enamel specimens forming an artificial interproximal space. The volunteers rinsed their mouths for 28 days, twice a day with the respective mouthrinse and brushed their teeth at least twice a day with a fluoride-free dentifrice. The specimens were cleaned once a day to simulate the use of dental floss. For analysis methods transversal microradiography, fluoride content measurement and quantitative light-induced fluorescence were used.

RESULTS: Mineral gain was significantly higher after the use of the fluoride mouthrinse: 571.88 Vol.% x microm (+/- 79.33 Vol.% x microm SEM) compared to the placebo treatment 51.14 Vol.% x microm (+/- 72.14 Vol.% x microm SEM). Significantly more fluoride uptake was observed after using the fluoride mouthrinse: 3666.39 microg/cm3 (+/- 513.50 microg/cm3 SEM) than after the placebo mouthrinse: 516.95 microg/cm3 (+/- 75.83 microg/cm3 SEM). The quantitative light-induced fluorescence showed a significant remineralizing effect after the fluoride treatment: -388.47 % x mm2 (+/- 18.76% x mm2 SEM) compared to the placebo treatment -27.88% x mm2 (+/- 20.19% x mm2 SEM).

Medienart:

Artikel

Erscheinungsjahr:

2007

Erschienen:

2007

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

American journal of dentistry - 20(2007), 6 vom: 12. Dez., Seite 385-9

Sprache:

Englisch

Beteiligte Personen:

Altenburger, Markus Jörg [VerfasserIn]
Schirrmeister, Jörg Fabian [VerfasserIn]
Wrbas, Karl-Thomas [VerfasserIn]
Hellwig, Elmar [VerfasserIn]

Themen:

8ZYQ1474W7
Amine fluoride solution
Cariostatic Agents
Comparative Study
Fluorides
Fluorides, Topical
Journal Article
Mouthwashes
Placebos
Q80VPU408O
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Sodium Fluoride

Anmerkungen:

Date Completed 08.04.2008

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM177564393