Masked clozapine-induced cardiomyopathy

A 33-year-old Latin-American woman with a history of psychosis and mood disorder, but no cardiac history or risk factors, presented with heart failure after 6 weeks of clozapine and olanzapine therapy. Her presentation was ambiguous and further complicated by a highly suggestible nature, which delayed the proper diagnosis and treatment. After discontinuing the antipsychotic agents and completing an otherwise negative comprehensive work-up, her heart function significantly improved (left ventricular ejection fraction increased from 38% to 53%). A literature search showed that cardiomyopathy secondary to antipsychotics has been reported but remains poorly understood. This is the second documented case report of clozapine-induced cardiomyopathy in a Latin-American woman.

Medienart:

E-Artikel

Erscheinungsjahr:

2008

Erschienen:

2008

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

Journal of the American Board of Family Medicine : JABFM - 21(2008), 1 vom: 01. Jan., Seite 70-4

Sprache:

Englisch

Beteiligte Personen:

Pastor, Charles A [VerfasserIn]
Mehta, Monica [VerfasserIn]

Links:

Volltext

Themen:

12794-10-4
Antipsychotic Agents
Benzodiazepines
Case Reports
Clozapine
J60AR2IKIC
Journal Article
N7U69T4SZR
Olanzapine

Anmerkungen:

Date Completed 20.03.2008

Date Revised 01.12.2018

published: Print

Citation Status MEDLINE

doi:

10.3122/jabfm.2008.01.070091

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM176709266