Seroprevalence of hepatitis E virus in blood donors in Khuzestan Province, southwest Iran
OBJECTIVE: To determine the seroprevalence of hepatitis E virus (HEV) infection among volunteer blood donors in Khuzestan Province, Iran. Khuzestan is a war stricken area in the southwest of Iran, which shares a land, river, and sea border with Iraq. This region has suffered the heaviest public health system damage of all the Iranian provinces during a 25-year period of war and conflict.
METHODS: A cross-sectional study was carried out among 400 urban volunteer blood donors of the regional blood banks, from May to December 2005. Serum samples from healthy blood donors were tested for IgG anti-HEV antibody using a specific enzyme linked immunoassay (ELISA) kit.
RESULTS: The prevalence of HEV infection was found to be 11.5% (46/400). All patients were negative for anti-HIV, anti-HBV, and anti-HCV antibodies. The data indicate that 14.6% (38/260) of HEV positive subjects were male, compared to 5.7% (8/140) of females; this difference is statistically significant (risk ratio=2.6, p<0.008).
CONCLUSIONS: These findings demonstrate the high prevalence rate of anti-HEV among blood donors, particularly males.
Medienart: |
Artikel |
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Erscheinungsjahr: |
2008 |
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Erschienen: |
2008 |
Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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Enthalten in: |
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 12(2008), 4 vom: 15. Juli, Seite 387-90 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Assarehzadegan, Mohammad Ali [VerfasserIn] |
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Themen: |
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Anmerkungen: |
Date Completed 14.10.2008 Date Revised 16.06.2008 published: Print-Electronic Citation Status MEDLINE |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM175592772 |
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100 | 1 | |a Assarehzadegan, Mohammad Ali |e verfasserin |4 aut | |
245 | 1 | 0 | |a Seroprevalence of hepatitis E virus in blood donors in Khuzestan Province, southwest Iran |
264 | 1 | |c 2008 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
338 | |a Band |b nc |2 rdacarrier | ||
500 | |a Date Completed 14.10.2008 | ||
500 | |a Date Revised 16.06.2008 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a OBJECTIVE: To determine the seroprevalence of hepatitis E virus (HEV) infection among volunteer blood donors in Khuzestan Province, Iran. Khuzestan is a war stricken area in the southwest of Iran, which shares a land, river, and sea border with Iraq. This region has suffered the heaviest public health system damage of all the Iranian provinces during a 25-year period of war and conflict | ||
520 | |a METHODS: A cross-sectional study was carried out among 400 urban volunteer blood donors of the regional blood banks, from May to December 2005. Serum samples from healthy blood donors were tested for IgG anti-HEV antibody using a specific enzyme linked immunoassay (ELISA) kit | ||
520 | |a RESULTS: The prevalence of HEV infection was found to be 11.5% (46/400). All patients were negative for anti-HIV, anti-HBV, and anti-HCV antibodies. The data indicate that 14.6% (38/260) of HEV positive subjects were male, compared to 5.7% (8/140) of females; this difference is statistically significant (risk ratio=2.6, p<0.008) | ||
520 | |a CONCLUSIONS: These findings demonstrate the high prevalence rate of anti-HEV among blood donors, particularly males | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Research Support, Non-U.S. Gov't | |
700 | 1 | |a Shakerinejad, Ghodratollah |e verfasserin |4 aut | |
700 | 1 | |a Amini, Akram |e verfasserin |4 aut | |
700 | 1 | |a Rezaee, S A Rahim |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |d 1998 |g 12(2008), 4 vom: 15. Juli, Seite 387-90 |w (DE-627)NLM094730857 |x 1878-3511 |7 nnns |
773 | 1 | 8 | |g volume:12 |g year:2008 |g number:4 |g day:15 |g month:07 |g pages:387-90 |
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