Use of weekly alendronate to treat osteoporosis in boys with muscular dystrophy
Three boys with muscular dystrophy with known osteoporosis were each treated for 1 yr with weekly alendronate and daily calcium and vitamin D. Measurements of lumbar spine and proximal femur using dual-energy x-ray absorptiometry were obtained at the initiation of the alendronate, at 6 mos, and at 1 yr. All three boys demonstrated increases in bone mineral density, with z scores improving from baseline to 1-yr follow-up. Improvements were observed at the lumbar spine, femoral neck, and greater trochanter. In this small case series, weekly oral alendronate for 1 yr plus daily vitamin D and calcium was effective in improving bone mineral density.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2008 |
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| Erschienen: |
2008 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
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| Enthalten in: |
American journal of physical medicine & rehabilitation - 87(2008), 2 vom: 01. Feb., Seite 139-43 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Apkon, Susan [VerfasserIn] |
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| Themen: |
1406-16-2 |
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| Anmerkungen: |
Date Completed 19.03.2008 Date Revised 18.10.2016 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM174155514 |
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| 245 | 1 | 0 | |a Use of weekly alendronate to treat osteoporosis in boys with muscular dystrophy |
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| 500 | |a Date Revised 18.10.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Three boys with muscular dystrophy with known osteoporosis were each treated for 1 yr with weekly alendronate and daily calcium and vitamin D. Measurements of lumbar spine and proximal femur using dual-energy x-ray absorptiometry were obtained at the initiation of the alendronate, at 6 mos, and at 1 yr. All three boys demonstrated increases in bone mineral density, with z scores improving from baseline to 1-yr follow-up. Improvements were observed at the lumbar spine, femoral neck, and greater trochanter. In this small case series, weekly oral alendronate for 1 yr plus daily vitamin D and calcium was effective in improving bone mineral density | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
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