Arterial distensibility in Wegener's granulomatosis : a carotid-femoral pulse wave velocity study
OBJECTIVE: The purpose of this study was to test the hypothesis; that chronic inflammation may impair vascular function and lead to an increase of arterial pulse wave velocity (PWV) in patients with Wegener's granulomatosis (WG).
METHODS: We recruited 5 patients with WG and 5 healthy age and sex matched controls in this cross-sectional case-controlled study. Aortic PWV was determined by using an automatic device (Complior Colson, France), which allowed on-line pulse wave recording and automatic calculation of PWV.
RESULTS: The carotid-femoral (aortic) PWV was increased in patients with WG as compared with control group (p=0.04). Although we found positive correlation between PWV and heart rate (r=0.75, p=0.01), we did not find any significant correlation between PWV and anthropometric and other hemodynamic parameters (p>0.05). In addition, we found positive correlation between PWV and erythrocyte sedimentation rate in patients with WG (r=0.90, p=0.03).
CONCLUSION: Pulse wave velocity is increased and arterial distensibility decreased in patients with WG. Measurements of carotid-femoral (aortic) PWV may provide an easy and noninvasive technique to identify patients at increased risk of arterial disease.
| Errataetall: |
CommentIn: Anadolu Kardiyol Derg. 2007 Sep;7(3):286. - PMID 17785218 |
|---|---|
| Medienart: |
Artikel |
| Erscheinungsjahr: |
2007 |
|---|---|
| Erschienen: |
2007 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:7 |
|---|---|
| Enthalten in: |
Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology - 7(2007), 3 vom: 06. Sept., Seite 281-5 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Yildiz, Mustafa [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 30.11.2007 Date Revised 24.11.2016 published: Print CommentIn: Anadolu Kardiyol Derg. 2007 Sep;7(3):286. - PMID 17785218 Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM172958865 |
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| 100 | 1 | |a Yildiz, Mustafa |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Arterial distensibility in Wegener's granulomatosis |b a carotid-femoral pulse wave velocity study |
| 264 | 1 | |c 2007 | |
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| 500 | |a Date Completed 30.11.2007 | ||
| 500 | |a Date Revised 24.11.2016 | ||
| 500 | |a published: Print | ||
| 500 | |a CommentIn: Anadolu Kardiyol Derg. 2007 Sep;7(3):286. - PMID 17785218 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: The purpose of this study was to test the hypothesis; that chronic inflammation may impair vascular function and lead to an increase of arterial pulse wave velocity (PWV) in patients with Wegener's granulomatosis (WG) | ||
| 520 | |a METHODS: We recruited 5 patients with WG and 5 healthy age and sex matched controls in this cross-sectional case-controlled study. Aortic PWV was determined by using an automatic device (Complior Colson, France), which allowed on-line pulse wave recording and automatic calculation of PWV | ||
| 520 | |a RESULTS: The carotid-femoral (aortic) PWV was increased in patients with WG as compared with control group (p=0.04). Although we found positive correlation between PWV and heart rate (r=0.75, p=0.01), we did not find any significant correlation between PWV and anthropometric and other hemodynamic parameters (p>0.05). In addition, we found positive correlation between PWV and erythrocyte sedimentation rate in patients with WG (r=0.90, p=0.03) | ||
| 520 | |a CONCLUSION: Pulse wave velocity is increased and arterial distensibility decreased in patients with WG. Measurements of carotid-femoral (aortic) PWV may provide an easy and noninvasive technique to identify patients at increased risk of arterial disease | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Soy, Mehmet |e verfasserin |4 aut | |
| 700 | 1 | |a Kürüm, Turhan |e verfasserin |4 aut | |
| 700 | 1 | |a Yildiz, Banu Sahin |e verfasserin |4 aut | |
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