Nocturnal asthma

Nocturnal asthma is one of the difficult form of asthma. It is associated with significant decline in pulmonary function and increase of airway inflammation at night. The pathophysiological mechanisms underlying the nocturnal aggravation of asthma are intricate. The most important seem to be: nocturnal environmental allergens, exacerbation of airflows and circadian variations of bronchial hyperreactivity, beta adrenergic receptors polymorphism, increased vagal tone. Home PEF monitoring will allow an objective assessment of nocturnal asthma. The physician-patient partnership is important in educating the patient to manage nocturnal episodes. The chrono-therapeutic approach will usually include inhaled or oral corticosteroids with the addition of theophylline, long-acting beta agonists with timing of therapy to give adequate effect during the night.

Medienart:

Artikel

Erscheinungsjahr:

2006

Erschienen:

2006

Enthalten in:

Zur Gesamtaufnahme - volume:110

Enthalten in:

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 110(2006), 3 vom: 20. Juli, Seite 505-10

Sprache:

Rumänisch

Weiterer Titel:

Astmul nocturn

Beteiligte Personen:

Grigoraş, C [VerfasserIn]
Mihăescu, Tr [VerfasserIn]

Themen:

Adrenal Cortex Hormones
Adrenergic beta-Agonists
Bronchodilator Agents
C137DTR5RG
English Abstract
Journal Article
Receptors, Adrenergic, beta
Review
Theophylline

Anmerkungen:

Date Completed 07.08.2007

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM170911926