Inadequacy of thromboprophylaxis in hospitalized medical patients

BACKGROUND: The risk of venous thromboembolism (VTE) is high in hospitalized patients, however it can be reduced by adequate prophylaxis.

OBJECTIVE: To evaluate the adequacy of VTE prophylaxis in hospitalized medical patients.

METHODS: A cross-sectional study was performed in hospitalized patients with acute medical illnesses in 4 hospitals of Salvador.

RESULTS: We evaluated 226 consecutive patients: 15.5% in medical ICU, 79% > 40 years of age and 48% male. The majority (97%) had a least 1 risk factor (RF) for VTE, 79% had reduced mobility and 62% were diagnosed as having a RF at admission. Of the 208 prophylaxis candidates, 54% received some form of prophylaxis: unfractionated heparin (UFH) in 44%, low molecular weight heparin (LMWH) in 56% and mechanical methods in 2 patients. The utilization rate was similar in private and public hospitals. (51% vs. 49%), but LMWH was more common in private hospitals, without a residence program (97%), and UFH in the public ones (86%). LMWH was more frequently used than UFH in patients > 40 years of age, more often in Caucasian than in Black patients, and less frequently in those with contraindications for heparin. Of the 112 patients receiving prophylaxis, 63% received adequate dosages: LMWH in 95.2% and UFH in 20.4%. VTE prophylaxis was adequate in only 33.6% (70/208) of the patients.

CONCLUSION: Risk Factors for VTE were frequent in medical patients. There was considerable variability of the VTE prophylaxis prescribed in private and public hospitals. LMWH was used more appropriately than UFH. However, only a minority of patients candidates for prophylaxis, received adequate dosages.

Medienart:

Artikel

Erscheinungsjahr:

2006

Erschienen:

2006

Enthalten in:

Zur Gesamtaufnahme - volume:52

Enthalten in:

Revista da Associacao Medica Brasileira (1992) - 52(2006), 6 vom: 07. Nov., Seite 441-6

Sprache:

Portugiesisch

Weiterer Titel:

Inadequação de tromboprofilaxia venosa em pacientes clínicos hospitalizados

Beteiligte Personen:

Rocha, Ana Thereza C [VerfasserIn]
Braga, Priscila [VerfasserIn]
Ritt, Guilherme [VerfasserIn]
Lopes, Antônio Alberto [VerfasserIn]

Themen:

9005-49-6
Anticoagulants
English Abstract
Heparin
Heparin, Low-Molecular-Weight
Journal Article

Anmerkungen:

Date Completed 30.08.2007

Date Revised 17.09.2019

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM167877275