Large-scale synthesis of immunoactivating natural product, pristane, by continuous microfluidic dehydration as the key step
An efficient protocol of dehydration was developed under microfluidic conditions. The method was applied to a multikilogram synthesis of pristane, a biologically important natural product, which is now widely used as an adjuvant for monoclonal antibody production. [reaction: see text].
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2007 |
|---|---|
| Erschienen: |
2007 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
|---|---|
| Enthalten in: |
Organic letters - 9(2007), 2 vom: 18. Jan., Seite 299-302 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Tanaka, Katsunori [VerfasserIn] |
|---|
| Themen: |
26HZV48DT1 |
|---|
| Anmerkungen: |
Date Completed 19.03.2007 Date Revised 15.11.2012 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
|
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| PPN (Katalog-ID): |
NLM167643738 |
|---|
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| 245 | 1 | 0 | |a Large-scale synthesis of immunoactivating natural product, pristane, by continuous microfluidic dehydration as the key step |
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| 500 | |a Date Revised 15.11.2012 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a An efficient protocol of dehydration was developed under microfluidic conditions. The method was applied to a multikilogram synthesis of pristane, a biologically important natural product, which is now widely used as an adjuvant for monoclonal antibody production. [reaction: see text] | ||
| 650 | 4 | |a Journal Article | |
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| 700 | 1 | |a Koyama, Koichi |e verfasserin |4 aut | |
| 700 | 1 | |a Tanaka, Shin-ichi |e verfasserin |4 aut | |
| 700 | 1 | |a Fukase, Koichi |e verfasserin |4 aut | |
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