Potential cytotoxic activity of some Brazilian seaweeds on human melanoma cells
Copyright (c) 2006 John Wiley & Sons, Ltd..
In vitro screening of the crude extracts of some Brazilian coastal seaweeds for cytotoxic activity against a cultured human melanoma cancer cell line using the sulphorhodamine B assay was performed. The crude dichloromethane:chloroform extract of Stypopodium zonale showed good cytotoxic activity against the C32 cell line. The crude acetone extract and aqueous phase of Lobophora variegata did not show any activity, but semi-purified fractions XAD LOB I and II could inhibit the growth of melanoma cells. The crude acetone extract of Caulerpa racemosa showed some cytotoxicity, but caulerpin isolated from this extract did not show any such activity. The crude acetone extract of Spatoglossum schroederi was not able to inhibit the growth of C32 melanoma cells.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2007 |
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| Erschienen: |
2007 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
|---|---|
| Enthalten in: |
Phytotherapy research : PTR - 21(2007), 2 vom: 30. Feb., Seite 170-5 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rocha, Fabíola Dutra [VerfasserIn] |
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| Themen: |
Antineoplastic Agents, Phytogenic |
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| Anmerkungen: |
Date Completed 08.05.2007 Date Revised 17.03.2022 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM166857181 |
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| 245 | 1 | 0 | |a Potential cytotoxic activity of some Brazilian seaweeds on human melanoma cells |
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| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright (c) 2006 John Wiley & Sons, Ltd. | ||
| 520 | |a In vitro screening of the crude extracts of some Brazilian coastal seaweeds for cytotoxic activity against a cultured human melanoma cancer cell line using the sulphorhodamine B assay was performed. The crude dichloromethane:chloroform extract of Stypopodium zonale showed good cytotoxic activity against the C32 cell line. The crude acetone extract and aqueous phase of Lobophora variegata did not show any activity, but semi-purified fractions XAD LOB I and II could inhibit the growth of melanoma cells. The crude acetone extract of Caulerpa racemosa showed some cytotoxicity, but caulerpin isolated from this extract did not show any such activity. The crude acetone extract of Spatoglossum schroederi was not able to inhibit the growth of C32 melanoma cells | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 7 | |a Antineoplastic Agents, Phytogenic |2 NLM | |
| 650 | 7 | |a Plant Extracts |2 NLM | |
| 700 | 1 | |a Soares, Angélica Ribeiro |e verfasserin |4 aut | |
| 700 | 1 | |a Houghton, Peter John |e verfasserin |4 aut | |
| 700 | 1 | |a Pereira, Renato Crespo |e verfasserin |4 aut | |
| 700 | 1 | |a Kaplan, Maria Auxiliadora Coelho |e verfasserin |4 aut | |
| 700 | 1 | |a Teixeira, Valéria Laneuville |e verfasserin |4 aut | |
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