The role of actomyosin and the microtubular network in both the immunological synapse and T cell activation
The formation of immunological synapses between T cells and APCs, as well as the functions associated with this structure, like cytokine secretion and the lysis of infected cells, are critical processes in the immune response. The T cell cytoskeleton is involved in these activities and this has been the subject of numerous studies in recent years. Although the importance of the T cell actin network is evident, the participation of microtubules and myosin motors in the formation of immunological synapses and T cell effector functions has also been assessed. This review provides an update on the role of cytoskeletal networks and related molecules in the activation of T lymphocytes.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2007 |
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| Erschienen: |
2007 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
Frontiers in bioscience : a journal and virtual library - 12(2007) vom: 01. Jan., Seite 437-47 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Rey, Mercedes [VerfasserIn] |
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| Themen: |
9013-26-7 |
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| Anmerkungen: |
Date Completed 23.08.2007 Date Revised 02.09.2019 published: Electronic Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM166800090 |
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| 100 | 1 | |a Rey, Mercedes |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The role of actomyosin and the microtubular network in both the immunological synapse and T cell activation |
| 264 | 1 | |c 2007 | |
| 336 | |a Text |b txt |2 rdacontent | ||
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| 500 | |a Date Completed 23.08.2007 | ||
| 500 | |a Date Revised 02.09.2019 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The formation of immunological synapses between T cells and APCs, as well as the functions associated with this structure, like cytokine secretion and the lysis of infected cells, are critical processes in the immune response. The T cell cytoskeleton is involved in these activities and this has been the subject of numerous studies in recent years. Although the importance of the T cell actin network is evident, the participation of microtubules and myosin motors in the formation of immunological synapses and T cell effector functions has also been assessed. This review provides an update on the role of cytoskeletal networks and related molecules in the activation of T lymphocytes | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Cytokines |2 NLM | |
| 650 | 7 | |a Actomyosin |2 NLM | |
| 650 | 7 | |a 9013-26-7 |2 NLM | |
| 700 | 1 | |a Sanchez-Madrid, Francisco |e verfasserin |4 aut | |
| 700 | 1 | |a Valenzuela-Fernandez, Agustin |e verfasserin |4 aut | |
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