The role of IL-6/sIL-6R complex and its natural inhibitor sgp130 in modulation of inflammatory process
IL-6/sIL-6R complex belongs to one of the most pleiotropic ligand-receptor system. Participating in leukocytes migration and apoptosis it plays a crucial role in modulation of inflammatory process. Firstly it contributes to resolution of acute inflammatory response regulating a maintaining of organism's homeostasis. Secondly it is a main factor responsible for transition between acute and chronic inflammatory reaction, that underlies the pathogenesis of chronic inflammatory diseases. Presented work focus on the IL-6/sIL-6R structure, function, formation, mechanism of action as well as the role of its natural inhibitor sgp130 in mentioned processes.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2006 |
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| Erschienen: |
2006 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:52 |
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| Enthalten in: |
Postepy biochemii - 52(2006), 2 vom: 14., Seite 194-203 |
| Sprache: |
Polnisch |
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| Weiterer Titel: |
Rola kompleksu IL-6/sIL-6R oraz jego naturalnego inhibitora sgp130 w modulowaniu procesu zapalnego |
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| Beteiligte Personen: |
Augustyniak, Daria [VerfasserIn] |
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| Themen: |
133483-10-0 |
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| Anmerkungen: |
Date Completed 28.12.2006 Date Revised 02.11.2006 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM166340464 |
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| 245 | 1 | 4 | |a The role of IL-6/sIL-6R complex and its natural inhibitor sgp130 in modulation of inflammatory process |
| 246 | 3 | 3 | |a Rola kompleksu IL-6/sIL-6R oraz jego naturalnego inhibitora sgp130 w modulowaniu procesu zapalnego |
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| 500 | |a Date Completed 28.12.2006 | ||
| 500 | |a Date Revised 02.11.2006 | ||
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a IL-6/sIL-6R complex belongs to one of the most pleiotropic ligand-receptor system. Participating in leukocytes migration and apoptosis it plays a crucial role in modulation of inflammatory process. Firstly it contributes to resolution of acute inflammatory response regulating a maintaining of organism's homeostasis. Secondly it is a main factor responsible for transition between acute and chronic inflammatory reaction, that underlies the pathogenesis of chronic inflammatory diseases. Presented work focus on the IL-6/sIL-6R structure, function, formation, mechanism of action as well as the role of its natural inhibitor sgp130 in mentioned processes | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a IL6ST protein, human |2 NLM | |
| 650 | 7 | |a Immunologic Factors |2 NLM | |
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| 700 | 1 | |a Jankowski, Adam |e verfasserin |4 aut | |
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