Treatment outcome of patients with multidrug-resistant pulmonary tuberculosis during pregnancy

PURPOSE: To know the treatment outcome of patients with multidrug-resistant tuberculosis (MDR-TB) during gestation.

METHOD: Retrospective study of 3 cases of pregnant women, who were treated for MDR-TB with a regimen including pyrazinamide, ethambutol, para-aminosalicylic acid, cycloserine and amoxicillin-clavulanic acid.

RESULT: All patients showed a good response to anti-tuberculosis chemotherapy without any serious adverse effect, and were culture-negative at the time of delivery. Two patients delivered vaginally at weeks 40, and one patient delivered surgically at weeks 38. All newborns were healthy, and their tuberculin skin tests and placental tissue examinations were negative for tuberculosis.

CONCLUSION: MDR-TB can be successfully treated during pregnancy by using a regimen including effective second-line anti-tuberculosis drugs.

Medienart:

Artikel

Erscheinungsjahr:

2006

Erschienen:

2006

Enthalten in:

Zur Gesamtaufnahme - volume:81

Enthalten in:

Kekkaku : [Tuberculosis - 81(2006), 6 vom: 09. Juni, Seite 413-8

Sprache:

Japanisch

Beteiligte Personen:

Takashima, Tetsuya [VerfasserIn]
Danno, Katsura [VerfasserIn]
Tamura, Yoshitaka [VerfasserIn]
Nagai, Takayuki [VerfasserIn]
Matsumoto, Tomoshige [VerfasserIn]
Han, Yuki [VerfasserIn]
Ano, Hiromi [VerfasserIn]
Yoshida, Hiroko [VerfasserIn]
Kawahara, Kunimitsu [VerfasserIn]
Tsuyuguchi, Izuo [VerfasserIn]

Themen:

2KNI5N06TI
5B2658E0N2
74469-00-4
8G167061QZ
95IK5KI84Z
Aminosalicylic Acid
Amoxicillin-Potassium Clavulanate Combination
Antitubercular Agents
Case Reports
Cycloserine
English Abstract
Ethambutol
Journal Article
Pyrazinamide

Anmerkungen:

Date Completed 25.07.2006

Date Revised 21.11.2013

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM164111220