Familial occurrence of diprosopus in German Holstein calves

Diprosopus was diagnosed in six German Holstein calves born on different dairy farms. The degree of facial duplication varied from a partial doubling of the nostrils and upper jaw to complete duplication of the face with formation of two mouths, four eyes and four ears. Further calves descending from the same parents or dams and calves from the same farms were not affected. A joint pedigree was ascertained for the calves with diprosopus. Furthermore, a previously reported case of diprosopus could be traced back to the same ancestors of this pedigree. Consequently, we detected the first time a familial accumulation of diprosopus. Since the ancestors showed no signs of diprosopus and the frequency of diprosopus in German Holsteins is presumably low, an oligogenic inheritance is likely. Recessive genes or a combination of recessive and dominant genes may cause this anomaly.

Medienart:

Artikel

Erscheinungsjahr:

2006

Erschienen:

2006

Enthalten in:

Zur Gesamtaufnahme - volume:119

Enthalten in:

Berliner und Munchener tierarztliche Wochenschrift - 119(2006), 5-6 vom: 26. Mai, Seite 251-7

Sprache:

Deutsch

Weiterer Titel:

Familiäres Auftreten von Diprosopus bei Kälbern der Rasse Deutsche Holsteins

Beteiligte Personen:

Schulze, Ursula [VerfasserIn]
Kuiper, Heidi [VerfasserIn]
Doeleke, Renate [VerfasserIn]
Ulrich, Reiner [VerfasserIn]
Gerdwilker, Axel [VerfasserIn]
Distl, Ottmar [VerfasserIn]

Themen:

Case Reports
Comparative Study
English Abstract
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Anmerkungen:

Date Completed 17.09.2007

Date Revised 29.05.2006

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM163083304