Clinical correlation of the CLSI susceptibility breakpoint for piperacillin- tazobactam against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella species

We assessed infections caused by extended-spectrum-beta-lactamase-producing Escherichia coli or Klebsiella spp. treated with piperacillin-tazobactam to determine if the susceptibility breakpoint predicts outcome. Treatment was successful in 10 of 11 nonurinary infections from susceptible strains and in 2 of 6 infections with MICs of >16/4 mug/ml. All six urinary infections responded to treatment regardless of susceptibility.

Medienart:

Artikel

Erscheinungsjahr:

2006

Erschienen:

2006

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Antimicrobial agents and chemotherapy - 50(2006), 6 vom: 24. Juni, Seite 2244-7

Sprache:

Englisch

Beteiligte Personen:

Gavin, Patrick J [VerfasserIn]
Suseno, Mira T [VerfasserIn]
Thomson, Richard B [VerfasserIn]
Gaydos, J Michael [VerfasserIn]
Pierson, Carl L [VerfasserIn]
Halstead, Diane C [VerfasserIn]
Aslanzadeh, Jaber [VerfasserIn]
Brecher, Stephen [VerfasserIn]
Rotstein, Coleman [VerfasserIn]
Brossette, Stephen E [VerfasserIn]
Peterson, Lance R [VerfasserIn]

Themen:

157044-21-8
87-53-6
Anti-Bacterial Agents
Beta-Lactamase Inhibitors
Comparative Study
Journal Article
Penicillanic Acid
Piperacillin
Piperacillin, Tazobactam Drug Combination
Research Support, Non-U.S. Gov't
X00B0D5O0E

Anmerkungen:

Date Completed 01.08.2006

Date Revised 01.12.2018

published: Print

Citation Status MEDLINE

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM163026858