Empirical antifungal therapy in selected patients with persistent fever and neutropenia
Empirical antifungal treatment (EAT) in neutropenia is mainly aimed at improving the poor prognosis of patients with invasive fungal infection through early treatment. The Infectious Diseases Society of America recommends initiating EAT in patients with persistent fever after 5-7 days of antibacterial treatment, and in those in whom remission of neutropenia is not imminent. Nevertheless, EAT has not been shown to be more effective than a placebo, it does not show better results than directed antifungal treatment, its effectiveness is minimal, it is not innocuous, and it is not very efficient with the use of most antifungal agents. All considered, we believe that the aforementioned recommendation for EAT treatment is unjustified. In its place we propose the application of EAT in patients selected on the basis of clinical criteria and risk factors.
| Medienart: |
Artikel |
|---|
| Erscheinungsjahr: |
2005 |
|---|---|
| Erschienen: |
2005 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
|---|---|
| Enthalten in: |
Enfermedades infecciosas y microbiologia clinica - 23(2005), 10 vom: 30. Dez., Seite 609-14 |
| Sprache: |
Spanisch |
|---|
| Weiterer Titel: |
Tratamiento antifúngico empírico en pacientes seleccionados con fiebre persistente y neutropenia |
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| Beteiligte Personen: |
Cisneros, José Miguel [VerfasserIn] |
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| Themen: |
Antifungal Agents |
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| Anmerkungen: |
Date Completed 13.04.2006 Date Revised 22.09.2019 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM159279739 |
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| 245 | 1 | 0 | |a Empirical antifungal therapy in selected patients with persistent fever and neutropenia |
| 246 | 3 | 3 | |a Tratamiento antifúngico empírico en pacientes seleccionados con fiebre persistente y neutropenia |
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| 500 | |a Date Completed 13.04.2006 | ||
| 500 | |a Date Revised 22.09.2019 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Empirical antifungal treatment (EAT) in neutropenia is mainly aimed at improving the poor prognosis of patients with invasive fungal infection through early treatment. The Infectious Diseases Society of America recommends initiating EAT in patients with persistent fever after 5-7 days of antibacterial treatment, and in those in whom remission of neutropenia is not imminent. Nevertheless, EAT has not been shown to be more effective than a placebo, it does not show better results than directed antifungal treatment, its effectiveness is minimal, it is not innocuous, and it is not very efficient with the use of most antifungal agents. All considered, we believe that the aforementioned recommendation for EAT treatment is unjustified. In its place we propose the application of EAT in patients selected on the basis of clinical criteria and risk factors | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 7 | |a Antifungal Agents |2 NLM | |
| 650 | 7 | |a Antineoplastic Agents |2 NLM | |
| 700 | 1 | |a Espigado, Ildefonso |e verfasserin |4 aut | |
| 700 | 1 | |a Rivero, Antonio |e verfasserin |4 aut | |
| 700 | 1 | |a Lozano de León, Fernando |e verfasserin |4 aut | |
| 700 | 1 | |a Parra, Jorge |e verfasserin |4 aut | |
| 700 | 1 | |a Collado, Antonio Ramón |e verfasserin |4 aut | |
| 700 | 1 | |a Lomas, José Manuel |e verfasserin |4 aut | |
| 700 | 1 | |a Pachón, Jerónimo |e verfasserin |4 aut | |
| 700 | 0 | |a Sociedad Andaluza de Enfermedades Infecciosas |e verfasserin |4 aut | |
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