Cost-effectiveness of liquid-based cytology with or without hybrid-capture II HPV test compared with conventional Pap smears : a study by the French Society of Clinical Cytology
Many articles concerning conventional Pap smears, ThinPrep liquid-based cytology (LBC) and Hybrid-Capture II HPV test (HC II) have been published. This study, carried out by the French Society of Clinical Cytology, may be conspicuous for several reasons: it was financially independent; it compared the efficiency of the conventional Pap smear and LBC, of the conventional Pap smear and HC II, and included an economic study based on real costs; for all the women, a "gold standard" reference method, colposcopy, was available and biopsies were performed whenever a lesion was detected; The conventional Pap smear, the LBC (split-sample technique), the colposcopy, and the biopsies were done at the same time. This study included 2,585 women shared into two groups: a group A of a high-risk population, a group B of a screening population. The statistical analysis of the results showed that conventional Pap smears consistently had superior or equivalent sensitivity and specificity than LBC for the lesions at threshold CIN-I (Cervical Intraepithelial Neoplasia) or CIN-II or higher. It underlined the low specificity of the HC II. Finally, the LBC mean cost was never covered by the Social Security tariff.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2005 |
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| Erschienen: |
2005 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
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| Enthalten in: |
Diagnostic cytopathology - 33(2005), 5 vom: 15. Nov., Seite 338-43 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Cochand-Priollet, Béatrix [VerfasserIn] |
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| Themen: |
Comparative Study |
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| Anmerkungen: |
Date Completed 28.02.2006 Date Revised 07.12.2022 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM158495373 |
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| 245 | 1 | 0 | |a Cost-effectiveness of liquid-based cytology with or without hybrid-capture II HPV test compared with conventional Pap smears |b a study by the French Society of Clinical Cytology |
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| 500 | |a Date Completed 28.02.2006 | ||
| 500 | |a Date Revised 07.12.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Many articles concerning conventional Pap smears, ThinPrep liquid-based cytology (LBC) and Hybrid-Capture II HPV test (HC II) have been published. This study, carried out by the French Society of Clinical Cytology, may be conspicuous for several reasons: it was financially independent; it compared the efficiency of the conventional Pap smear and LBC, of the conventional Pap smear and HC II, and included an economic study based on real costs; for all the women, a "gold standard" reference method, colposcopy, was available and biopsies were performed whenever a lesion was detected; The conventional Pap smear, the LBC (split-sample technique), the colposcopy, and the biopsies were done at the same time. This study included 2,585 women shared into two groups: a group A of a high-risk population, a group B of a screening population. The statistical analysis of the results showed that conventional Pap smears consistently had superior or equivalent sensitivity and specificity than LBC for the lesions at threshold CIN-I (Cervical Intraepithelial Neoplasia) or CIN-II or higher. It underlined the low specificity of the HC II. Finally, the LBC mean cost was never covered by the Social Security tariff | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
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| 700 | 1 | |a de Cremoux, Patricia |e verfasserin |4 aut | |
| 700 | 1 | |a Le Galès, Catherine |e verfasserin |4 aut | |
| 700 | 1 | |a Ziol, Marianne |e verfasserin |4 aut | |
| 700 | 1 | |a Molinié, Vincent |e verfasserin |4 aut | |
| 700 | 1 | |a Petitjean, Alain |e verfasserin |4 aut | |
| 700 | 1 | |a Dosda, Anne |e verfasserin |4 aut | |
| 700 | 1 | |a Merea, Estelle |e verfasserin |4 aut | |
| 700 | 1 | |a Biaggi, Annonciade |e verfasserin |4 aut | |
| 700 | 1 | |a Gouget, Isabelle |e verfasserin |4 aut | |
| 700 | 1 | |a Arkwright, Sylviane |e verfasserin |4 aut | |
| 700 | 1 | |a Vacher-Lavenu, Marie-Cécile |e verfasserin |4 aut | |
| 700 | 1 | |a Vielh, Philippe |e verfasserin |4 aut | |
| 700 | 1 | |a Coste, Joël |e verfasserin |4 aut | |
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