Papillon-Lefèvre syndrome treated with acitretin
A 7-year-old boy born to consanguineous parents had suffered from palmoplantar keratoderma and chronic gingivitis since the age of 3 months. He was diagnosed with Papillon-Lefèvre syndrome. Genetic testing confirmed that he was homozygous with a point mutation in exon 6 of the cathepsin C gene. One year after initiating treatment with acitretin 10 mg oral daily and trimethoprim-sulfamethoxazole, the patient's skin remains almost lesion-free, and he has new teeth that erupted during treatment and are free of periodontal disease.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2005 |
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| Erschienen: |
2005 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:46 |
|---|---|
| Enthalten in: |
The Australasian journal of dermatology - 46(2005), 3 vom: 15. Aug., Seite 199-201 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Lee, Michael R [VerfasserIn] |
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| Themen: |
Acitretin |
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| Anmerkungen: |
Date Completed 26.10.2005 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM156460785 |
|---|
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| 245 | 1 | 0 | |a Papillon-Lefèvre syndrome treated with acitretin |
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| 500 | |a Date Completed 26.10.2005 | ||
| 500 | |a Date Revised 21.11.2013 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A 7-year-old boy born to consanguineous parents had suffered from palmoplantar keratoderma and chronic gingivitis since the age of 3 months. He was diagnosed with Papillon-Lefèvre syndrome. Genetic testing confirmed that he was homozygous with a point mutation in exon 6 of the cathepsin C gene. One year after initiating treatment with acitretin 10 mg oral daily and trimethoprim-sulfamethoxazole, the patient's skin remains almost lesion-free, and he has new teeth that erupted during treatment and are free of periodontal disease | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Keratolytic Agents |2 NLM | |
| 650 | 7 | |a Acitretin |2 NLM | |
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| 700 | 1 | |a Wong, Li-Chuen F |e verfasserin |4 aut | |
| 700 | 1 | |a Fischer, Gayle O |e verfasserin |4 aut | |
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