Medium-sized peptides as built in carriers for biologically active compounds
(c) 2005 Wiley Periodicals, Inc. Med Res Rev..
A growing number of oligopeptides of natural and/or synthetic origin have been described and considered as targeting structures for delivery bioactive compounds into various cell types. This review will outline the discovery of peptide sequences and the corresponding mid-sized oligopeptides with membrane translocating properties and also summarize de novo designed structures possessing similar features. Conjugates and chimera constructs derived from these sequences with covalently attached bioactive peptide, epitope, oligonucleotide, PNA, drug, reporter molecule will be reviewed. A brief note will refer to the present understanding on the uptake mechanism at the end of each section.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2005 |
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| Erschienen: |
2005 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
|---|---|
| Enthalten in: |
Medicinal research reviews - 25(2005), 6 vom: 01. Nov., Seite 679-736 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Hudecz, Ferenc [VerfasserIn] |
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| Anmerkungen: |
Date Completed 23.03.2006 Date Revised 18.11.2010 published: Print Citation Status MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM155928139 |
|---|
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| 245 | 1 | 0 | |a Medium-sized peptides as built in carriers for biologically active compounds |
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| 500 | |a Date Completed 23.03.2006 | ||
| 500 | |a Date Revised 18.11.2010 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a (c) 2005 Wiley Periodicals, Inc. Med Res Rev. | ||
| 520 | |a A growing number of oligopeptides of natural and/or synthetic origin have been described and considered as targeting structures for delivery bioactive compounds into various cell types. This review will outline the discovery of peptide sequences and the corresponding mid-sized oligopeptides with membrane translocating properties and also summarize de novo designed structures possessing similar features. Conjugates and chimera constructs derived from these sequences with covalently attached bioactive peptide, epitope, oligonucleotide, PNA, drug, reporter molecule will be reviewed. A brief note will refer to the present understanding on the uptake mechanism at the end of each section | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a Review | |
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