Parathyroid hormone-mediated regulation of renal phosphate co-transporter
The key player in proximal tubular Pi reabsorption, the type IIa Na(+)/Pi co-transporter, is internalized upon PTH treatment and degraded in the lysosomes. PTH action is initiated by apically and basolaterally localized PTH receptors, whereby apical effects are most probably via cAMP-independent (via PKC) and basolateral effects via cAMP-dependent (via PKA) regulatory mechanisms. The molecular determinants at the level of the transporter protein or at the level of interacting (regulatory) proteins are not yet known.
| Medienart: |
Artikel |
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| Erscheinungsjahr: |
2001 |
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| Erschienen: |
2001 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
Clinical calcium - 11(2001), 12 vom: 19. Dez., Seite 1612-6 |
| Sprache: |
Japanisch |
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| Beteiligte Personen: |
Morita, K [VerfasserIn] |
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| Themen: |
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| Anmerkungen: |
Date Completed 10.05.2005 Date Revised 15.11.2006 published: Print Citation Status PubMed-not-MEDLINE |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM154288438 |
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| 003 | DE-627 | ||
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| 008 | 231223s2001 xx ||||| 00| ||jpn c | ||
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| 041 | |a jpn | ||
| 100 | 1 | |a Morita, K |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Parathyroid hormone-mediated regulation of renal phosphate co-transporter |
| 264 | 1 | |c 2001 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ohne Hilfsmittel zu benutzen |b n |2 rdamedia | ||
| 338 | |a Band |b nc |2 rdacarrier | ||
| 500 | |a Date Completed 10.05.2005 | ||
| 500 | |a Date Revised 15.11.2006 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a The key player in proximal tubular Pi reabsorption, the type IIa Na(+)/Pi co-transporter, is internalized upon PTH treatment and degraded in the lysosomes. PTH action is initiated by apically and basolaterally localized PTH receptors, whereby apical effects are most probably via cAMP-independent (via PKC) and basolateral effects via cAMP-dependent (via PKA) regulatory mechanisms. The molecular determinants at the level of the transporter protein or at the level of interacting (regulatory) proteins are not yet known | ||
| 650 | 4 | |a English Abstract | |
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Iida, M |e verfasserin |4 aut | |
| 700 | 1 | |a Takeda, E |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Clinical calcium |d 1996 |g 11(2001), 12 vom: 19. Dez., Seite 1612-6 |w (DE-627)NLM093766858 |x 0917-5857 |7 nnns |
| 773 | 1 | 8 | |g volume:11 |g year:2001 |g number:12 |g day:19 |g month:12 |g pages:1612-6 |
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